Results 91 to 100 of about 341,043 (301)

Ultrasmall Platinum Nanoparticles for Radiation‐Enhanced Cancer Therapy

open access: yesAdvanced Functional Materials, EarlyView.
This work proposes a nanomedicine‐based strategy to enhance X‐ray radiotherapy for cancer treatment. Ultrasmall Pt‐NPs exhibit catalase‐like activity that may contribute to modulation of the tumor microenvironment and amplify interactions between radiation and biological matter, leading to increased DNA damage.
Miguel Encinas‐Gimenez   +8 more
wiley   +1 more source

Towards sustainable management of rodents in organic animal husbandry [PDF]

open access: yes, 2004
From 26 to 28 May 2004 an international seminar was held in Wageningen, the Netherlands, about current knowledge and advice on rodent management on organic pig and poultry farms in Western Europe. This paper summarizes the discussions.
Kijlstra, Aize, Meerburg, Bastiaan
core  

Identifying wildlife reservoirs of neglected taeniid tapeworms : non-invasive diagnosis of endemic Taenia serialis infection in a wild primate population [PDF]

open access: yes, 2017
Despite the global distribution and public health consequences of Taenia tapeworms, the life cycles of taeniids infecting wildlife hosts remain largely undescribed.
Beehner, Jacinta C   +11 more
core   +3 more sources

Translational Considerations for Injectable Biomaterials and Bioscaffolds to Repair and Regenerate Brain Tissue

open access: yesAdvanced Healthcare Materials, EarlyView.
The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley   +1 more source

Borrelia burgdorferi Manipulates Innate and Adaptive Immunity to Establish Persistence in Rodent Reservoir Hosts. [PDF]

open access: yes, 2017
Borrelia burgdorferi sensu lato species complex is capable of establishing persistent infections in a wide variety of species, particularly rodents. Infection is asymptomatic or mild in most reservoir host species, indicating successful co-evolution of ...
Baumgarth, Nicole, Tracy, Karen E
core   +1 more source

Lysosome‐Acidifying Nanoparticles Rescue A30P α‐Synuclein Induced Neuronal Death in Cellular and Drosophila Models of Parkinson's Disease

open access: yesAdvanced Healthcare Materials, EarlyView.
Lysosome‐targeted acidic nanoparticles based on a biodegradable poly(ethylene tetrafluorosuccinate‐co‐succinate) copolymer are engineered to restore impaired lysosomal acidification through pH‐responsive intracellular degradation. Localized acid release enhances autophagic proteolysis, reduces α‐synuclein accumulation, and preserves dopaminergic neuron
Chih Hung Lo   +6 more
wiley   +1 more source

A Community-Based Surveillance on Determinants of Rodent Infestation

open access: yesKaohsiung Journal of Medical Sciences, 2003
Rodent infestation is an important factor in the transmission of infectious diseases of public health importance. From October to November 1998, surveillance stations were established in 110 boroughs of Kaohsiung City in southern Taiwan.
Hsiu-Hua Pai
doaj   +1 more source

CD28 between tolerance and autoimmunity: The side effects of animal models [version 1; referees: 2 approved] [PDF]

open access: yes, 2018
Regulation of immune responses is critical for ensuring pathogen clearance and for preventing reaction against self-antigens. Failure or breakdown of immunological tolerance results in autoimmunity.
A Aruffo   +57 more
core   +2 more sources

A Personalized, 3D Printed Polymeric Device for the Prevention of Post‐Myocardial Infarction Cardiac Remodeling

open access: yesAdvanced Healthcare Materials, EarlyView.
Myocardial infarction often leads to pathological remodelling and ventricular dilatation, key features of HFrEF. This study introduces a personalized, 3D‐printed cardiac restraint device (CARD) printed using rationally designed inks displaying the requested printability and mechanical properties.
Nicola Mansour   +6 more
wiley   +1 more source

A single rapamycin dose protects against late-stage experimental cerebral malaria via modulation of host immunity, endothelial activation and parasite sequestration

open access: yesMalaria Journal, 2017
Background Maladaptive immune responses during cerebral malaria (CM) result in high mortality despite opportune anti-malarial chemotherapy. Rapamycin, an FDA-approved immunomodulator, protects against experimental cerebral malaria (ECM) in mice through ...
Pedro Mejia   +6 more
doaj   +1 more source

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