Results 81 to 90 of about 211,794 (261)

Inhibition of VEGF‐Induced Angiogenesis and Vascular Leakage by Bicistronic Co‐Expression of Aflibercept and COMP‐Ang1

Advanced Healthcare Materials, EarlyView.
A bicistronic rAAV8 vector encoding Aflibercept (Afb) and COMP‐cAng1 simultaneously coordinates VEGF clearance and Tie2‐mediated vessel maturation. In a 3D angiogenesis‐on‐a‐chip model, rAAV8‐Afb/cAng1 effectively reverses pathological barrier breakdown under clinical disease‐mimicking challenges.
Bong‐Kyu Kim, Jaehong Min, Sang‐Hee Park, Subeen Shin, Sangbin Yu, Jeong‐Eun Park, Sujin Kim, Wooju Park, Jihoon Ko, Sunjong Kwon   +9 more
wiley   +1 more source

Multiwavelength Implantable Oximeter for Wireless Monitoring of Tissue Oxygenation in the Presence of Blood Volume Changes

Advanced Healthcare Materials, EarlyView.
This study presents an implantable, wireless, battery‐free oximeter that can continuously monitor physiologically consistent regional tissue oxygenation under dynamic changes of blood volume. This is achieved through multiwavelength photoplethysmography and validated both via Monte Carlo simulations and in vivo rat studies. Different stress events were
Anat Usatinsky, Hugo L. Higueros‐Garcia, Sadi Loai, Samantha Unger, Jacob Trueb, Yonatan Usatinsky, Rawad Alkallas‐Valdiviezo, Noor Abu Jarad, Jonathan Wu, Hai‐Ling M. Cheng, John A. Rogers, Abraham Vázquez‐Guardado, Daniel Franklin   +12 more
wiley   +1 more source

Rodent species composition in urban and forested areas in eastern Germany [PDF]

Biodiversity Data Journal
Zoonoses are major concerns for public health and after the recent pandemic, have been under a global spotlight for their often unpredictable spread and rapid evolution.
Jasmin Firozpoor, Riccardo Gardini, Mario Escobar Huezo, Jana Eccard   +3 more
doaj   +3 more sources

Effectiveness of Ficus benjamina “Vaditi” and Artocarpus treculianus Elm. “Tipuho” Sap Extracts as Non-Chemical Rodent Trap

JPAIR, 2020
Pests are organisms that can cause economic damage or become threats to the health of humans and domestic animals. Rodents are pests and are considered to be essential reservoirs of numerous diseases that infect humans, domestic animals, and other ...
William Jo Se Billote, Paul Alcantara, Dean Eduard Cadid, Keenen Ivory Delos Reyes, Aira Marie Entela, Maria Angelica Gabotero, Ryan Ponce   +6 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Systematic surveillance tools to reduce rodent pests in disadvantaged urban areas can empower communities and improve public health

Scientific Reports
Rodents are notorious pests, known for transmitting major public health diseases and causing agricultural and economic losses. The lack of site-specific and national standardised rodent surveillance in several disadvantaged communities has rendered ...
Adedayo Michael Awoniyi, Ana Maria Barreto, Hernan Dario Argibay, Juliet Oliveira Santana, Fabiana Almerinda G. Palma, Ana Riviere-Cinnamond, Gauthier Dobigny, Eric Bertherat, Luther Ferguson, Steven Belmain, Federico Costa   +10 more
doaj   +1 more source

Use of rodents as models of human diseases

Journal of Pharmacy And Bioallied Sciences, 2014
Advances in molecular biology have significantly increased the understanding of the biology of different diseases. However, these discoveries have not yet been fully translated into improved treatments for patients with diseases such as cancers. One of the factors limiting the translation of knowledge from preclinical studies to the clinic has been the
openaire   +3 more sources

Advanced Materials for Biologics Delivery to Brain Tumors

Advanced Materials, EarlyView.
Material innovation is central to unlocking the therapeutic potential of biologics against many central nervous system diseases, including brain cancer. By engineering carriers with controlled transport, targeting, and release properties, advanced materials can overcome the blood–brain barrier and tumor microenvironment, improving the delivery of ...
Yuran Feng, Yuxue Cao, Maria Kavallaris, Taskeen Janjua, Amirali Popat   +4 more
wiley   +1 more source

The Hidden Threat: Rodent-Borne Viruses and Their Impact on Public Health

Viruses
Rodents represent the most diverse order of mammals, comprising over 2200 species and nearly 42% of global mammalian biodiversity. They are major reservoirs of zoonotic pathogens, including viruses, bacteria, protozoa, and fungi, and are particularly ...
Awad A. Shehata, Rokshana Parvin, Shadia Tasnim, Phelipe Magalhães Duarte, Alfonso J. Rodriguez-Morales, Shereen Basiouni   +5 more
doaj   +1 more source

Tumbling Magnetic Microrobots for Targeted In Vivo Drug Delivery in the GI Tract

Advanced Robotics Research, EarlyView.
We introduce a microrobot design and integrated system for on‐demand targeted drug release in the gastrointestinal tract. The microrobot has an embedded magnet for actuation with external magnetic fields and is visualized in real time using ultrasound. It has two drug release ports sealed with a thermally sensitive wax. Local heating of the wax using a
Aaron C. Davis, Luis Carlos Sanjuan Acosta, Shubh P. Mehta, Baiyan Qi, Yang Yang, Luis Solorio, Craig J. Goergen, David J. Cappelleri   +7 more
wiley   +1 more source