Protection against filovirus diseases by a novel broad-spectrum nucleoside analogue BCX4430
Nature, 2014 Filoviruses are emerging pathogens and causative agents of viral haemorrhagic fever. Case fatality rates of filovirus disease outbreaks are among the highest reported for any human pathogen, exceeding 90% (ref. 1).
Travis K Warren +19 more
semanticscholar +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
Advanced Science, EarlyView.This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li +3 more
wiley +1 more source
A survey of Nairobi sheep disease antibody in sheep and goats, wild ruminants and rodents within Kenya [PDF]
, 1978 F. G. Davies
openalex +1 more source
Achieving inter- and transdisciplinarity in Ecohealth: insights from a rodent-borne disease project in a polycrisis era. [PDF]
Front Vet SciIntroductionInter- and transdisciplinary research (ITDR) is increasingly promoted to address “wicked problems”, particularly in health sectors adopting approaches like Ecohealth.
Arpin I +16 more
europepmc +2 more sources
Rational Design of Inner Ear Drug Delivery Systems
Advanced Science, EarlyView.Hearing loss is a common disease affecting many people, and inner ear lesions are one of the most important causes. This review focuses on the treatment of inner ear hearing loss by drug delivery systems. It includes the current methods and technologies developed, and it predicts possible directions.
Xiayidan Maimaitikelimu +5 more
wiley +1 more source
Use of large animal models to investigate Huntington's diseases
Cell Regeneration, 2019 Animal models that can mimic human diseases are the important tools for investigating the pathogenesis of the diseases and finding a way for treatment.
Sen Yan, Shihua Li, Xiao-Jiang Li
doaj
Identification of endemic foci of Lyme disease: isolation of Borrelia burgdorferi from feral rodents and ticks (Dermacentor variabilis) [PDF]
, 1985 John F. Anderson +3 more
openalex +1 more source
Current status of plague and plague control in the United States [PDF]
, 1970 During the first quarter of the 20th century, massive rat-borne plague epidemics occurred in port cities of the United States in conjunction with the last world-wide pandemic which originated in China in 1893.
Barnes, Allan M., Poland, Jack D.
core +1 more source
IncRNA‐ZFAS1, an Emerging Gate‐Keeper in DNA Damage‐Dependent Transcriptional Regulation
Advanced Science, EarlyView.LncZFAS1 plays a crucial role during DNA damage response in mammalian cells. Loss of lncZFAS1 results in deficient DNA lesion removal and reduced cell viability. Mechanistically, lncZFAS1 modulates RNAPII phosphorylation and transcription and thereby promotes both GG‐NER and TC‐NER upon UV damage.
Jiena Liu +10 more
wiley +1 more source
Pharmacology of boldine: summary of the field and update on recent advances
Frontiers in PharmacologyOver the past decade, boldine, a naturally occurring alkaloid found in several plant species including the Chilean Boldo tree, has garnered attention for its efficacy in rodent models of human disease.
Juan C. Sáez +32 more
doaj +1 more source