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Parkinson’s disease: a rethink of rodent models
Experimental Brain Research, 2006Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from genetic risk factors, environmental exposures and most likely a combination of both. Rodent models of parkinsonism aim to reproduce key pathogenic features of the syndrome including movement disorder induced by the progressive loss of dopaminergic neurons in ...
Heather L, Melrose +3 more
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In Practice, 2010
Pet rodents make up a small but significant part of the caseload in small animal veterinary practice. Skin disease is a frequent reason for presentation, as it is easily noticed by the owner, even in species that are not regularly handled. Particular problems encountered with the diagnosis and treatment of skin disease in rodents include the stress of ...
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Pet rodents make up a small but significant part of the caseload in small animal veterinary practice. Skin disease is a frequent reason for presentation, as it is easily noticed by the owner, even in species that are not regularly handled. Particular problems encountered with the diagnosis and treatment of skin disease in rodents include the stress of ...
openaire +1 more source
Cortical Plasticity in Alzheimer’s Disease in Humans and Rodents
Biological Psychiatry, 2007The aim of this study was to determine whether neocortical long-term potentiation (LTP) is deficient in patients with Alzheimer's disease (AD) and in amyloid precursor protein (APP)/presenilin-1 (PS1) mice, an AD animal model. We then ascertained whether this deficit might be paralleled by functional abnormalities of N-methyl-D-aspartate (NMDAR ...
BATTAGLIA F +6 more
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Genetic Rodent Models of Huntington Disease
2018The monogenic nature of Huntington disease (HD) has led to the development of a spectrum of useful genetically modified models. In particular, rodents have pioneered as the first HD model being generated and have since been the most widely used animal model for HD in both basic research and preclinical therapeutic studies.
J, Stricker-Shaver +3 more
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Rodents in Relation to Disease and Their Control
Journal of the Royal Army Medical Corps, 1949openaire +2 more sources
Superwarfarin Rodent Poisons and Hemorrhagic Disease
Epidemiology, 2012Yirong, Fang +9 more
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