Results 11 to 20 of about 10,821,016 (340)

Effect of rodent density on tick and tick-borne pathogen populations: consequences for infectious disease risk

Parasites & Vectors, 2020
Background Rodents are considered to contribute strongly to the risk of tick-borne diseases by feeding Ixodes ricinus larvae and by acting as amplifying hosts for pathogens. Here, we tested to what extent these two processes depend on rodent density, and
Aleksandra I. Krawczyk, Gilian L. A. van Duijvendijk, Arno Swart, Dieter Heylen, Ryanne I. Jaarsma, Frans H. H. Jacobs, Manoj Fonville, Hein Sprong, Willem Takken   +8 more
doaj   +2 more sources

Rodent Models of Nonalcoholic Fatty Liver Disease [PDF]

Digestion, 2019
Background: Nonalcoholic fatty liver disease (NAFLD) is a continuous diseases spectrum associated with obesity, type 2 diabetes, insulin resistance, and hyperlipidemia.
F. Zhong, Xiaoming Zhou, Jin Xu, Ling Gao   +3 more
semanticscholar   +3 more sources

Mapping global risk of bat and rodent borne disease outbreaks to anticipate emerging threats [PDF]

Scientific Reports
Future epidemics and/or pandemics may likely arise from zoonotic viruses with bat- and rodent-borne pathogens being among the prime candidates. To improve preparedness and prevention strategies, we predicted the global distribution of bat- and rodent ...
Soushieta Jagadesh, Claudia Cataldo, Wim Van Bortel, Esther Van Kleef, William Wint, Annapaola Rizzoli, Luca Busani, Elena Arsevska   +7 more
doaj   +2 more sources

Rodent species composition in urban and forested areas in eastern Germany [PDF]

Biodiversity Data Journal
Zoonoses are major concerns for public health and after the recent pandemic, have been under a global spotlight for their often unpredictable spread and rapid evolution.
Jasmin Firozpoor, Riccardo Gardini, Mario Escobar Huezo, Jana Eccard   +3 more
doaj   +4 more sources

Validation of Reference Genes via qRT-PCR in Multiple Conditions in Brandt’s Voles, Lasiopodomys brandtii

Animals, 2021
The choice of optimal reference gene is challenging owing to the varied expression of reference genes in different organs, development stages, and experimental treatments. Brandt’s vole (Lasiopodomys brandtii) is an ideal animal to explore the regulatory
Lin Tian, Yan Chen, Da-Wei Wang, Xiao-Hui Liu   +3 more
doaj   +1 more source

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

Nature Communications, 2023
Microglial activation plays central roles in neuroinflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18 kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative ...
E. Nutma, N. Fancy, M. Weinert, S. Tsartsalis, M. Marzin, R. Muirhead, Irene Falk, M. Breur, Joy de Bruin, David Hollaus, Robin Pieterman, J. Anink, David J. Story, S. Chandran, Jiabin Tang, M. C. Trolese, T. Saito, T. Saido, Katharine H. Wiltshire, Paula Beltran-Lobo, Alexandra E. M. Phillips, J. Antel, Luke M. Healy, Marie-France Dorion, D. Galloway, Rochelle Y. Benoit, Quentin Amossé, Kelly Ceyzériat, Aurélien M. Badina, E. Kövari, C. Bendotti, E. Aronica, Carola I. Radulescu, J. Wong, A. Barron, Amy M. Smith, Samuel J. Barnes, D. Hampton, P. Van Der Valk, S. Jacobson, O. Howell, D. Baker, M. Kipp, Hannes Kaddatz, B. Tournier, P. Millet, P. Matthews, C. Moore, S. Amor, D. Owen   +49 more
semanticscholar   +1 more source

No Evidence for the Presence of SARS-CoV-2 in Bank Voles and Other Rodents in Germany, 2020–2022

Pathogens, 2022
Rodentia is the most speciose mammalian order, found across the globe, with some species occurring in close proximity to humans. Furthermore, rodents are known hosts for a variety of zoonotic pathogens. Among other animal species, rodents came into focus
Kerstin Wernike, Stephan Drewes, Calvin Mehl, Christin Hesse, Christian Imholt, Jens Jacob, Rainer G. Ulrich, Martin Beer   +7 more
doaj   +1 more source

Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

bioRxiv, 2022
Microglial activation plays central roles in neuro-inflammatory and neurodegenerative diseases. Positron emission tomography (PET) targeting 18kDa Translocator Protein (TSPO) is widely used for localising inflammation in vivo, but its quantitative ...
E. Nutma, N. Fancy, M. Weinert, M. Marzin, S. Tsartsalis, R. Muirhead, Irene Falk, Joy de Bruin, David Hollaus, Robin Pieterman, J. Anink, David J. Story, S. Chandran, Jiabin Tang, M. C. Trolese, T. Saito, T. Saido, Katie M. Wiltshire, Paula Beltran-Lobo, Alexandra Philips, J. Antel, Luke M. Healy, C. Moore, C. Bendotti, E. Aronica, Carola I. Radulescu, Samuel J. Barnes, D. Hampton, P. Van Der Valk, S. Jacobson, P. Matthews, S. Amor, D. Owen   +32 more
semanticscholar   +1 more source

Knowledge, attitude, and preventive practices toward rodent-borne diseases in Ngorongoro district, Tanzania

Journal of Public Health in Africa, 2023
In addition to their economic significance, rodents are hosts and transmit diseases. Most of rodent-borne diseases are endemic in rural Africa and sporadically lead to epidemics.
Amina Issae, Augustino Chengula, Rose Kicheleri, Christopher Kasanga, Abdul Katakweba   +4 more
doaj   +1 more source

Behavioral tests for evaluating the characteristics of brain diseases in rodent models: Optimal choices for improved outcomes (Review).

Molecular Medicine Reports, 2022
Behavioral assessment is the dominant approach for evaluating whether animal models of brain diseases can successfully mimic the clinical characteristics of diseases.
Lingyi Huang, Dongqiong Xiao, Hao Sun, Y. Qu, Xiaojuan Su   +4 more
semanticscholar   +1 more source