Results 231 to 240 of about 211,794 (261)

Overview on Rodent Models of Alzheimer's Disease

Current Protocols in Neuroscience, 2005
AbstractIn Alzheimer's disease (AD), characteristic lesions develop in brain regions that subserve cognitive functions, ultimately leading to dementia. There are now several lesioned or transgenic small‐animal models of the disease that model select aspects of cognitive deficits and/or recapitulate many, but not all, of the characteristic pathologic ...
Jean-Cosme, Dodart, Patrick, May
openaire   +2 more sources

Pharmacological Models of Parkinson’s Disease in Rodents

2011
Parkinson's disease (PD) is one of the most common neurodegenerative disorders. Despite the substantial progress that has been achieved, the precise mechanisms involved in the development of this disease are still not fully understood. The most common concepts relate to the genetic background and environmental/toxic effects.
Peter, Klivenyi, Laszlo, Vecsei
openaire   +2 more sources

Parkinson’s disease: a rethink of rodent models

Experimental Brain Research, 2006
Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from genetic risk factors, environmental exposures and most likely a combination of both. Rodent models of parkinsonism aim to reproduce key pathogenic features of the syndrome including movement disorder induced by the progressive loss of dopaminergic neurons in ...
Heather L, Melrose, Sarah J, Lincoln, Glenn M, Tyndall, Matthew J, Farrer   +3 more
openaire   +2 more sources

Skin diseases of rodents

In Practice, 2010
Pet rodents make up a small but significant part of the caseload in small animal veterinary practice. Skin disease is a frequent reason for presentation, as it is easily noticed by the owner, even in species that are not regularly handled. Particular problems encountered with the diagnosis and treatment of skin disease in rodents include the stress of ...
openaire   +1 more source

Cortical Plasticity in Alzheimer’s Disease in Humans and Rodents

Biological Psychiatry, 2007
The aim of this study was to determine whether neocortical long-term potentiation (LTP) is deficient in patients with Alzheimer's disease (AD) and in amyloid precursor protein (APP)/presenilin-1 (PS1) mice, an AD animal model. We then ascertained whether this deficit might be paralleled by functional abnormalities of N-methyl-D-aspartate (NMDAR ...
BATTAGLIA F, WANG HY, GHILARDI MF, GASHI E, QUARTARONE, Angelo, FRIEDMAN E, NIXON RA   +6 more
openaire   +2 more sources

Genetic Rodent Models of Huntington Disease

2018
The monogenic nature of Huntington disease (HD) has led to the development of a spectrum of useful genetically modified models. In particular, rodents have pioneered as the first HD model being generated and have since been the most widely used animal model for HD in both basic research and preclinical therapeutic studies.
J, Stricker-Shaver, A, Novati, L, Yu-Taeger, H P, Nguyen   +3 more
openaire   +2 more sources

Ecological interactions, local people awareness and practices on rodent-borne diseases in Africa: A review

Acta Tropica, 2023
Never Muboko, Annabel Banda
exaly  

Rodents in Relation to Disease and Their Control

Journal of the Royal Army Medical Corps, 1949
openaire   +2 more sources

Evidence for Quercetin as a Dietary Supplement for the Treatment of Cardio-Metabolic Diseases in Pregnancy: A Review in Rodent Models

Foods, 2022
Diego Lacerda, Paulo César Trindade da Costa, JOSÉ Luiz De Brito Alves   +2 more
exaly  

Transmission ecology of rodent‐borne diseases: New frontiers

Integrative Zoology, 2015
Kim Blasdell, Serge Morand
exaly