Results 131 to 140 of about 885,770 (382)

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.

Journal of Clinical Investigation, 2009
High dietary fat intake leads to insulin resistance in skeletal muscle, and this represents a major risk factor for type 2 diabetes and cardiovascular disease.
E. Anderson, Mary E. Lustig, K. Boyle, T. Woodlief, D. Kane, Chien‐Te Lin, J. W. Price, Li Kang, P. Rabinovitch, H. Szeto, J. Houmard, R. Cortright, D. Wasserman, P. Neufer   +13 more
semanticscholar   +1 more source

Biomimetic Scaffolds Enhance iPSC Astrocyte Progenitor Angiogenic, Immunomodulatory, and Neurotrophic Capacity in a Stiffness and Matrix‐Dependent Manner for Spinal Cord Repair Applications

Advanced Healthcare Materials, EarlyView.
Through tuning biomimetic scaffold stiffness and matrix composition the reparative capacity of astrocyte progenitors is enhanced. Soft, collagen‐IV/fibronectin‐functionalized scaffolds promote progenitor growth while improving angiogenic, immunomodulatory, and neurotrophic capacity in a stiffness and matrix‐dependent manner, demonstrating the impact of
Cian O'Connor, Ian Woods, Sarah F. McComish, Sean Kerr, Matthew McGrath, Juan Carlos Palomeque Chávez, Jack Maughan, Tara McGuire, Maeve A. Caldwell, Adrian Dervan, Fergal J. O'Brien   +10 more
wiley   +1 more source

Leucine aminopeptidase1 controls egg deposition and hatchability in male Aedes aegypti mosquitoes

Nature Communications
Aedes aegypti are vectors for several arboviruses infecting hundreds of millions of people annually. Controlling mosquito populations by regulating their reproduction is a potential strategy to minimize viral transmission in the absence of effective ...
Xiaomei Sun, Xueli Wang, Kai Shi, Xiangyang Lyu, Jian Sun, Alexander S. Raikhel, Zhen Zou   +6 more
doaj   +1 more source

Safety Evaluation of Repeated Application of Polymeric Microarray Patches in Miniature Pigs

Advanced Healthcare Materials, EarlyView.
This study demonstrates the safety of repeated application of three types of microarray patches (MAPs), hydrogelforming, dissolving, and implantable, over four weeks in miniature pigs. No adverse skin or systemic effects were observed, supporting the clinical potential of MAPs as safe and effective drug delivery platforms.
Qonita Kurnia Anjani, Aaron R. J. Hutton, Peter E. McKenna, Eneko Larrañeta, Ryan F. Donnelly   +4 more
wiley   +1 more source

Huddling remodels gut microbiota to reduce energy requirements in a small mammal species during cold exposure

Microbiome, 2018
Background Huddling is highly evolved as a cooperative behavioral strategy for social mammals to maximize their fitness in harsh environments. Huddling behavior can change psychological and physiological responses.
Xue-Ying Zhang, Gansukh Sukhchuluun, Ting-Bei Bo, Qing-Sheng Chi, Jun-Jie Yang, Bin Chen, Lei Zhang, De-Hua Wang   +7 more
doaj   +1 more source

Wasatch and Wind River rodents [PDF]

, 1907
F. B. Loomis
openalex   +1 more source

Medial frontal ∼4-Hz activity in humans and rodents is attenuated in PD patients and in rodents with cortical dopamine depletion.

Journal of Neurophysiology, 2015
The temporal control of action is a highly conserved and critical mammalian behavior. Here, we investigate the neuronal basis of this process using an interval timing task.
K. Parker, Kuan-Hua Chen, J. Kingyon, J. Cavanagh, N. Narayanan   +4 more
semanticscholar   +1 more source

Multifunctional Neural Probes Enable Bidirectional Electrical, Optical, and Chemical Recording and Stimulation In Vivo

Advanced Materials, EarlyView.
Convergence drawing is used to create flexible, microscale, multifunctional fiber‐based neural probes. Optimized materials selection enables individual devices to perform neural recording, electrical stimulation, optogenetics, fiber photometry, fluid delivery, and voltammetric neurotransmitter detection in rodents.
Nicolette Driscoll, Marc‐Joseph Antonini, Taylor M. Cannon, Pema Maretich, Greatness Olaitan, Valerie Doan Phi Van, Keisuke Nagao, Atharva Sahasrabudhe, Emmanuel Vargas Paniagua, Ethan J. Frey, Ye Ji Kim, Sydney Hunt, Melissa Hummel, Sanju Mupparaju, Alan Jasanoff, B. Jill Venton, Polina Anikeeva   +16 more
wiley   +1 more source

Quantitative inheritance of volatile pheromones and darcin and their interaction in olfactory preferences of female mice

Scientific Reports, 2017
In this study, we examined how urine-borne volatile compounds (UVCs) and darcin of male mice are inherited from parents and interact to modulate the olfactory preferences of females using two inbred strains of mice, C57Bl/6 (C57) and BALB/c (BALB), and ...
Ying-Juan Liu, Hui-Fen Guo, Jian-Xu Zhang, Yao-Hua Zhang   +3 more
doaj   +1 more source

On the Genera of Rodents: An Attempt to bring up to Date the current Arrangement of the Order . By Oldfield Thomas, F.Z.S. Proc. Zool. Soc., London, 1896, pp. 1012-1028. Issued April, 1897. [PDF]

, 1897
T. S. Palmer
openalex   +1 more source