Results 171 to 180 of about 2,281,205 (316)

Noninvasive Focal Gene Delivery into the Cerebellum of Non‐Human Primates using Focused Ultrasound

Advanced Science, EarlyView.
Focal and non‐invasive viral vector delivery in non‐human primates remains a major challenge in translational neuroscience. Low‐intensity focused ultrasound was used to transiently open the blood–brain barrier and enable targeted gene delivery to the cerebellum.
Noelia Esteban‐García, José A. Pineda‐Pardo, Inés Trigo‐Damas, Marta Gutiérrez, Marta Castillo‐Ortiz, Megan Carrillo, Alejandro Reinares‐Sebastian, Víctor Medina‐Chavarrías, Itay Rachmilevitch, Masahiko Takada, José A. Obeso, Javier Blesa   +11 more
wiley   +1 more source

Endocrine modulation of stimulant use: bidirectional interactions within the hypothalamic-pituitary-gonadal axis. [PDF]

Front Behav Neurosci
Huskinson SL, Kohtz AS.
europepmc   +1 more source

Aspects of the ecology of desert-living rodents in the North-East Badia region of Jordan. [PDF]

, 2000
Scott, Dawn Millicent
core  

Estimating body mass of fossil rodents

, 2013
Reconstructing the body mass of a fossil animal is an essential step toward understanding its palaeoecological role. Length × width (L×W) of the first lower molar (m1) is frequently used as a proxy for body mass in fossil mammals. However, among rodents,
Martín-Suárez, E., Freudenthal, M.
core  

Decoding the Mechanism of Action of a Parasite TGFβ Antagonist Inspires the Creation of Cell‐Type‐Specific TGFβ Modulators

Advanced Science, EarlyView.
The mammalian TGFβ interacts with ubiquitously expressed TGFBR1 and TGFBR2, and current TGFβ‐targeting agents are non‐cell‐selective. The cooperative interaction of the modular parasite TGFβ antagonist with multiple host (co‐)receptors empowers the design of TGM chimeras and bispecific antibodies that activate or inhibit TGFβ signaling in a cell ...
Maarten van Dinther, Tristin Schwartze, Jiying Zhang, Kun Fan, Gerard van der Zon, Luke Power, Cynthia S. Hinck, Claire Ciancia, Ananya Mukundan, Roman Gonzalez‐Prieto, Peter van Veelen, Rick M. Maizels, Andrew P. Hinck, Peter ten Dijke   +13 more
wiley   +1 more source

Assessment of Nontarget Small Mammal Occupancy Using Broadly Designed Camera Arrays. [PDF]

Ecol Evol
Olah AM, Ganoe LS, Hickling CJ, Bol TT, Ruggieri D, Mayer A, Carroll KA.   +6 more
europepmc   +1 more source

Diversity of Cryptosporidium from rodents in Thailand

, 2014
Species of Cryptosporidium are ubiquitous parasites capable of infecting numerous animal species and humans. Wild rodents are naturally infected by Cryptosporidium via contaminated environment.
Masakul, Amornrat, Chaisiri, Kittipong, Morand, Serge, Herder, Stéphane, Binot, Aurélie, Desquesnes, Marc, Thaprathom, Noppawan, Karnchanabanthoen, Anamika, Jittapalapong, Sathaporn   +8 more
core  

Prmt6 Deficiency or Inhibition Restores Microglial Homeostasis and Promotes Scar‐Limited Repair in Adult Spinal Cord Injury

Advanced Science, EarlyView.
After spinal cord injury, adult microglia remain persistently activated with chronic PRMT6 (protein arginine methyltransferase 6) upregulation. Prmt6 deficiency or inhibition reestablishes microglial homeostasis and promotes a scar‐limited repairment, enhancing axonal regrowth.
Weilin Peng, Zhengqiang Wu, Yu Xiong, Zhongya Gao, Yishan Liu, Ziyi Wang, Haibin Wang, Chaofeng Han, Wenxiang Chu, Xuhua Lu   +9 more
wiley   +1 more source

Encephalomyocarditis virus (EMCV): An overlooked threat to primates. [PDF]

PLoS Negl Trop Dis
Amona I, Kumakamba C, Labarrere C, Davoust B, Fenollar F, Mediannikov O.   +5 more
europepmc   +1 more source

Mechanosensitive Piezo1/Osteocalcin/Irisin Axis Protects Against Disuse‐Induced Muscle Atrophy

Advanced Science, EarlyView.
Mechanical unloading suppresses bone Piezo1 expression, which reduces circulating undercarboxylated osteocalcin (unOCN). unOCN reduction subsequently exacerbates IMM‐induced Fndc5/Irisin decrease and drives severe muscle atrophy. Bone Piezo1 activation or exogenous osteocalcin/Irisin ameliorate muscle atrophy, while muscle‐specific Gprc6a or Fndc5 ...
Zhaolu Wang, Xiuying Jiang, Xi Sun, Hao Chen, Jianjun Jin, Xin'e Shi   +5 more
wiley   +1 more source