Results 211 to 220 of about 2,707,765 (379)

Interactions of Antibody Drug Conjugate Anti‐Tubulin and Topoisomerase I Inhibitor Payloads with Radiotherapy to Potentiate Immunotherapy

Advanced Science, EarlyView.
Antibody drug conjugates deliver their cytotoxic anti‐tubulin or topoisomerase I inhibitor payloads to tumors through cancer cell receptor targeting. The released drug payloads induce cellular changes that interact with radiotherapy resulting in radiosensitization that improves cancer cell kill and stimulates anti‐tumor immune responses.
Jacqueline Lesperance, Bryan S. Yung, Michael M. Allevato, Marcus M Cheng, Maria F. Camargo, Robert Saddawi‐Konefka, Kanika Dhawan, Ashwyn K. Sharma, Mahsa Mortaja, Sophie Bice, Daniel J. Scanderbeg, Diego Alvarado, Jyoti Mayadev, Ramez N. Eskander, Stephen R. Adams, Pippa F. Cosper, J. Silvio Gutkind, Sunil J. Advani   +17 more
wiley   +1 more source

Why animal models are still needed for discoveries in mental health research. [PDF]

J Psychiatry Neurosci
Borgland S.
europepmc   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

Advanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao, Yijun Zhang, Hanyu Rao, Jiani Sun, Zhiyi Pan, Liping Jin, Yan Zhao   +6 more
wiley   +1 more source

Burden of rodent-borne viruses in rodents and zoonotic risk in humans in Cambodia. [PDF]

Microbiol Spectr
Guillebaud J, Nouhin J, Hul V, Hoem T, Yanneth O, Sim M, Khun L, Y P, Heng L, Ken S, Pum L, Lim R, Meng C, Chhel K, Nuon S, Hoem S, Nguon K, Chan M, Ly S, Karlsson EA, Reynes J-M, Sakunthabhai A, Dussart P, Duong V.   +23 more
europepmc   +1 more source

Interactive effects of exogenous and endogenous factors on demographic rates of an African rodent

, 2016
Chloé R. Nater, Cindy I. Canale, Koen J. van Benthem, Chi‐Hang Yuen, Ivana Schoepf, Neville Pillay, Arpat Özgül, Carsten Schradin   +7 more
openalex   +1 more source

Dysfunctional TRIM31 of POMC Neurons Provokes Hypothalamic Injury and Peripheral Metabolic Disorder under Long‐Term Fine Particulate Matter Exposure

Advanced Science, EarlyView.
Particulate matter ≤2.5 µm (PM2.5) elevates risks of neurological and chronic metabolic diseases, but the underlying mechanisms linking PM2.5‐induced central nervous system (CNS) injury to metabolic dysfunction remain unclear. Hypothalamic pro‐opiomelanocortin‐expressing (POMC+) neurons regulate systemic metabolic homeostasis, and tripartite motif ...
Chenxu Ge, Jiamao Lin, Changsheng Yang, Chuanwang Miao, Fengxiang Li, Shuqiang Zhao, Lei Zou, Xuedong Teng, Lina Liu, Tingguang Li, Yan Sun, Qiang Li, Deshuai Lou, Linfeng Hu, Xi Liu, Gang Kuang, Jing Luo, Minxuan Xu, Minghui Chang, Jun Tan, Yanrong Ren, Bochu Wang   +21 more
wiley   +1 more source

Factors Associated With <i>Toxoplasma gondii</i> Infection Among Pregnant Women Admitted for Delivery in Selected Hospitals in Dar es Salaam, Tanzania. [PDF]

Biomed Res Int
Liponda M, Ng Weshemi S, Munisi D.
europepmc   +1 more source

Mammals of South America. Volume 2: Rodents

Ameghiniana, 2016
M. E. Pérez, N. Upham
semanticscholar   +1 more source

1953 report of rodents research commission

, 1954
田中 英雄
openalex   +2 more sources

Gut Bacteria Improve Depressive Symptoms by Degrading Cortisol into Androgen

Advanced Science, EarlyView.
Chronic stress is an important risk factor for stress‐related disorders such as depression. Stress hormone cortisol is essential for the pathogenesis of stress‐related disorders such as depression. Some gut microbiota degraded cortisol, and improve depressive symptoms.
Xiong Wang, Qing Wu, Hao‐Long Zeng, Yin Shen, Hong‐Han Zhang, Jun Gong, Qi Zhang, Jia‐Zhao Xie, Da‐Wei Ye, Zi‐Yong Sun, Zhong‐Chun Liu, Li‐Ming Cheng, Di Li   +12 more
wiley   +1 more source