Species barriers in AAV tropism: mechanisms, models, and emerging solutions for clinical translation. [PDF]
Xu X.
europepmc +1 more source
Mammals of South America. Volume 2: Rodents
M. E. Pérez, N. Upham
semanticscholar +1 more source
Identifying Cytokine Motif‐Containing, Immunomodulatory Bacterial Proteins in Human Gut Microbiome
By building and constructing HMM (Upper left, blue), the authors identify CMCPs in bacteria genomes and CRC related metagenomes and enriched CRC‐related CMCPs (Upper right, blue). They analyze sequence and structural similarity of hits (Lower left, green), test function with engineered EcN delivered to tumors in a mouse tumor model (Lower right, pink ...
Ziyu Wang +12 more
wiley +1 more source
Mixed Signals and Interspecies Variation in the Plasticity of Adult Mammal Brains. [PDF]
Pattaro A +5 more
europepmc +1 more source
Sex differences in chronic stress effects on cognition in rodents
V. Luine, J. Gómez, K. Beck, R. Bowman
semanticscholar +1 more source
We studied how five common immunosuppressants behave when delivered directly to a transplant site instead of systemically. Using a vascularized implant for islet transplantation, we show that local delivery protects grafts, limits drug spread to the rest of the body, and produces distinct immune signatures.
Jocelyn Nikita Campa‐Carranza +19 more
wiley +1 more source
Mysterious Leishmania martiniquensis parasites and their relatives of the subgenus Mundinia: Emerging pathogens reshaping our understanding of leishmaniases. [PDF]
Volf P, Sadlova J.
europepmc +1 more source
Oil‐Coated Nanoplastics Induce Rapid Membrane Disruption and Severe Intestinal Injury
Oil‐rich food contact dramatically amplifies MNP release from plastic takeout containers, producing oil‐coated nanoplastics with altered surface properties and rapid membrane‐disruptive effects. These particles cause severe intestinal barrier damage and immune dysfunction in mice, and risk modeling suggests that long‐term gastrointestinal burdens may ...
Ruwen Xie +17 more
wiley +1 more source
An activity‐dependent pathway links prefrontal circuit hypoactivity to cognitive impairment. Reduced PVA–mPFC activity upregulates NEPAS, which suppresses PTX3 secretion, leading to impaired angiogenesis, myelin deficits, and memory decline. Rescue is achieved by NEPAS knockdown or chemogenetic circuit activation.
Boya Hu +11 more
wiley +1 more source
Molecular epidemiology of rodent-borne <i>Leptospira</i> spp. in Sri Lanka: identification of novel sequence types and previously unrecognized reservoir animals. [PDF]
Rathnayake N +10 more
europepmc +1 more source

