Results 211 to 220 of about 2,726,823 (350)

Translating the Habenula-From Rodents to Humans.

Biological Psychiatry, 2017
Laura-Joy Boulos, E. Darcq, B. Kieffer
semanticscholar   +1 more source

Endoplasmic Reticulum Geometry Dictates Neuronal Bursting via Calcium Store Refill Rates and Exposes Selective Neuronal Vulnerability

Advanced Science, EarlyView.
The ER's continuous tubular network is maintained by ER‐shaping proteins whose mutation or dysregulation contributes to neurodegenerative diseases. Here, we show that ER morphology sets the speed of Ca2+ store replenishment between firing events. Disrupting ER continuity slows intra‐ER Ca2+ redistribution from extracellular refill (SOCE) sites, driving
Valentina Davi, Pierre Parutto, Yuyi Zhang, Tasuku Konno, Cecile Crapart, Raquel Pereira, John P. Franklin, Mosab Ali Awadelkareem, Daniel C Maddison, Michael J. Devine, Edgar R. Gomes, Joseph Chambers, Elena Koslover, Edward Avezov   +13 more
wiley   +1 more source

Studies on prevalence of Hantavirus in small mammals in Southeast Asia: A systematic review and meta-analysis. [PDF]

PLoS Negl Trop Dis
Guo Z, Pan H, Wang N, Xiao Y, Zhang Q, Ren C, Liu P, Wu Q, Cai L, Cheng Y, Li W, Sun D.   +11 more
europepmc   +1 more source

Hepatocyte BDNF Acts as a Novel Immune Checkpoint to Restrain TLR4‐Mediated Acute Hepatitis

Advanced Science, EarlyView.
This study identifies hepatocyte‐derived BDNF as an endogenous TLR4 antagonist that alleviates acute hepatitis. BDNF is downregulated in hepatocytes via REST‐mediated transcriptional repression during ALI/ALF. Mechanistically, BDNF binds to TLR4 on macrophages to suppress inflammation.
Weiwei Zhu, Yaqian Cui, Yongqiang Zhou, Yihui Zheng, Lijiang Huang, Leiming Jin, Qianhui Zhang, Pan Chen, Mengsha Lin, Jiaxi Ye, Yongqiang Xiong, Joo Young Huh, Xiang Hu, Xiaokun Li, Wu Luo, Guang Liang   +15 more
wiley   +1 more source

Prevalence of antibodies against hantavirus, Leptospira, lymphocytic choriomeningitis virus and Chlamydia psittaci in pest control workers in Germany - a cross-sectional study. [PDF]

J Occup Med Toxicol
Barnekow T, Schablon A, Kleinmüller O, Nienhaus A.   +3 more
europepmc   +1 more source

Empathy for Distress in Humans and Rodents

Neuroscience Bulletin, 2018
Jun Chen
semanticscholar   +1 more source

Rodents [PDF]

, 1990
openaire   +1 more source

Persistently Increased Expression of PKMzeta and Unbiased Gene Expression Profiles Identify Hippocampal Molecular Traces of a Long‐Term Active Place Avoidance Memory and “Shadow” Proteins

Advanced Science, EarlyView.
Protein complexes like KIBRA‐PKMζ are crucial for maintaining memories, forming month‐long protein traces in memory‐tagged neurons, but conventional RNA‐seq analysis fails to detect their transcript changes, leaving memory molecules undetected in the shadows of abundantly‐expressed genes.
Jiyeon Han, Alejandro Grau‐Perales, Rayna M. Harris, Edith Lesburguères, Hsin‐Yi Kao, Asit Pal, Juan Marcos Alarcon, Todd C. Sacktor, Stefano Martiniani, Hans A. Hofmann, André A. Fenton   +10 more
wiley   +1 more source

An integrated surveillance in Zhejiang Province: ecological and pathogen survey of vectors and reservoir hosts in 2024. [PDF]

Front Vet Sci
Wang J, Luo M, Liu Q, Li T, Guan Z, Gong Z, Hou J, Sun J, Jiang J.   +8 more
europepmc   +1 more source

Mitochondrial H2O2 emission and cellular redox state link excess fat intake to insulin resistance in both rodents and humans.

Journal of Clinical Investigation, 2009
E. Anderson, Mary E. Lustig, K. Boyle, Tracey L. Woodlief, D. Kane, Chien‐Te Lin, J. W. Price, Li Kang, P. Rabinovitch, H. Szeto, J. Houmard, R. Cortright, D. Wasserman, P. Neufer   +13 more
semanticscholar   +1 more source