Results 101 to 110 of about 25,105,841 (305)
Le dioula véhiculaire : Situation sociolinguistique en Côte d’Ivoire
Our present article intends to present the role of vehicular dioula in Côte d’Ivoire. Indeed, many studies have already been made on the language in question, showing how the language is dynamic and important as well as economically and socially.
Konate Yaya
doaj +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
We present role logic, a notation for describing properties of relational structures in shape analysis, databases, and knowledge bases. We construct role logic using the ideas of de Bruijn's notation for lambda calculus, an encoding of first-order logic ...
Kuncak, Viktor, Rinard, Martin
core +5 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The role of participation and empowerment in income and poverty dynamics in Indonesia 1993-2000 [PDF]
The objective of this study is to assess whether living in a community that has a more democratic decision making system or in a society with a higher degree of participation and cooperation has any effect on household income changes and poverty ...
Anette Walstad Enes, Espen Villanger
core
The Role of Fort Asa City as a Basic Defense of The Bima Kingdom in 1667
The resistance of the Bima people in defending the kingdom's territory from Dutch colonial colonialism has taken quite a long time, where Asakota Fort has an important role as a maritime defense strategy.
Subari Subari, Anwar Anwar
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Integration of circadian and hypoxia signaling via non‐canonical heterodimerization
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley +1 more source
Role of Epidemiological Studies in Disease Prevention [PDF]
Today's society is full of disease that are of different natures including genetic, infectious and metabolic etc. Every disease has its own mechanisms of affecting humans and different prevention mechanisms as per disease nature.
Akthar, M. S. (Muhammad)
core

