Results 121 to 130 of about 17,822,863 (260)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Two- Level Role Theory and EU Migration

open access: yes
Applying role theory and Putnam’s two-level game framework to the European migration crisis of 2015, Magdalena Kozub-Karkut expertly shows how the Czech Republic, Slovakia, Hungary, and Poland used the crisis to contest their roles in the European Union (
Kozub- Karkut, Magdalena   +1 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Honor Role and Holy Rollers concert flier, d.c. Space, Washington, D.C., January 21, 1989

open access: yes, 1989
Flier promoting a concert by the punk bands Honor Role and Holy Rollers at d.c. Space in Washington D.C.

core  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

hifis.gitlab_runner Ansible role

open access: yes
Ansible role for deploying GitLab-Runner (optimized for use with Openstack)."If you use this Ansible role, please cite it as below.
Ziegner, Norman   +2 more
core   +3 more sources

Assessing Gender Dimorphism Indicators in Anthropometric Characteristics and Features of the Bony Pelvis of Female Representatives of Pair and Group Types in Sports Acrobatics

open access: yesPhysical Education Theory and Methodology
Objectives. The study aimed to examine individual anthropometric indicators, focusing on the bony pelvis size in female acrobats of various roles during the puberty and youth age, as well as in persons who do not engage in playing sports.
Nataliia Veronika Bachynska   +3 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Honor Role and Swiz flier - d.c. Space, Washington, D.C., June 25, 1987

open access: yes, 1987
Photocopy of an advertising flier promoting a concert by the Washington, D.C. punk band, Swiz. The concert occurred on June 25, 1987 at d.c. Space in Washington, D.C. The other band on the bill was Honor Role, a punk band from Richmond, Virginia.
Farrell, Jason (Musician)
core  

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

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