Results 101 to 110 of about 17,303,399 (256)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Pushing the Limit: The Role-Less Multirole Warship

open access: yes, 2019
Designing effective multirole vessels, particularly warships, is complicated by the potential for the roles, and the mix of roles, to change. Modularity is frequently suggested as an approach to addressing this problem.
Pawling, R, Bradbeer, N
core   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Rapid synthesis: Role and impacts of perioperative surgical-team assistants

open access: yes
An in-depth synthesis of what is known based on the best available global research evidence (i.e., evidence syntheses) and local research evidence (i.e., single studies) and may include a scan of experiences from other countries and from Canadian ...
Jaspal, A   +6 more
core  

The significance and perspectives of role playing as a teaching method in process oriented nursing education [PDF]

open access: yes, 1999
This study was to report the results of students' responses to role playing which has been introduced as a teaching method in adult nursing clinical practice.
冨岡, 詔子   +4 more
core  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Counseling Matters: A Multi-Case Study of High School Counselors and Their Perception of their Role in the School Community

open access: yes, 2010
WINDLE, MICHELLE HURT. Counseling Matters: A Multi-Case Study of High School Counselors and Their Perceptions of Their Role in the School Community. (Under the direction of Dr. Paul Bitting).
Windle, Michelle Hurt
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Effects of perceiver's sex-role orientation, target's sex-role preference and occupational choice on the attractiveness of competent women

open access: yes, 1982
The purpose of this study was to examine the relationship between the self-reported sex-role orientation of hale and female undergraduate college students and their perceived attraction to women with differing occupational choices (traditional vs ...
Mariatou-Metaxa, Eugenia
core  

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