Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan+10 more
wiley +1 more source
Barriers and Enablers to Leadership in Advanced Practice Nursing: A Systematic Review. [PDF]
Fosah R, Llahana S.
europepmc +1 more source
Low expression of five purine metabolism‐related genes (ADSL, APRT, ADCY3, NME3, NME6) was correlated with poor survival in colorectal cancer. Immunohistochemistry analysis showed that low NME3 (early stage) and low ADSL/NME6 (late stage) levels were associated with high risk.
Sungyeon Kim+8 more
wiley +1 more source
Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis [PDF]
BOCCHINO, MARIALUISA+4 more
core
NFAT5: a stress-related transcription factor with multiple functions in health and disease. [PDF]
Domínguez-López A+4 more
europepmc +1 more source
Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu+15 more
wiley +1 more source
The role of perception in divergent approaches to teaching and learning through the transition from foundation to bachelor degree: a preliminary exploration [PDF]
Corkill, H.
core
Exploring interventions to support life participation for adults with chronic kidney disease: a scoping review. [PDF]
Correa M, Hussam R, Farragher J.
europepmc +1 more source
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Artificial intelligence voice gender, gender role congruity, and trust in automated vehicles. [PDF]
Zhang Q, Yang XJ, Robert LP.
europepmc +1 more source