Results 151 to 160 of about 25,105,841 (305)

Role of mycobacteria-induced monocyte/macrophage apoptosis in the pathogenesis of human tuberculosis [PDF]

, 2005
BOCCHINO, MARIALUISA, BRUNETTI E., COLIZZI V, GALATI D, SANDUZZI ZAMPARELLI, ALESSANDRO   +4 more
core  

Managing role conflicts: work-study-life balance among single female university teachers in China pursuing doctoral degrees. [PDF]

Int J Qual Stud Health Well-being
Jia W, Boo HS.
europepmc   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Sex-Based Differences in Disease Burden and Phenotype in CADASIL: A Multicenter Study of 368 Korean Patients. [PDF]

Neurol Genet
Kim JG, Choi JC, Kang CH, Oh JH, Lee JS, Kang JH, Byeon S, Lim JS, Kim BJ, Kim H, Suh CH, Heo SH, Woo HG, Nam HS, Lee BC, Yu KH, Oh MS, Lee M, Kim CK, Oh K, Kang SH, Lee KJ, Han JH, Kim YS, Kim HY, Kim HJ, Bae HJ, Han MK, Kang J, Kim BJ, Kim JY, Lee SH, Jung KH, Sohn SI, Hong JH, Park H, Kwon JH, Kim WJ, Shin DI, Yum KS, Chae HY, Sung SM, Seo SW, Kim JP, Jung JM, Lee K, Park TH, Park SS, Choi JK, Park MS, Kim JT, Choi KH, Cha JK, Kim DH, Yoon BA, Lee SJ, Kim JG, Kim DH, Kim DE, Gwak DS, Kim C, Lee SH, Lee J, Kwon DH, Kang K, Park KY, Jeong HB, Park CY, Cho YJ, Hong KS, Park HK.   +70 more
europepmc   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

Understanding diverse subjectivities of medical students in seeking composite role models: A Q-methodology study. [PDF]

PLoS One
Hasani R, Mohammadi E, Norouzi A, Khabaz Mafinejad M.   +3 more
europepmc   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Latest advances on the role of P2X Receptors in colorectal inflammation and cancer. [PDF]

Purinergic Signal
Ruo L, Fortuna F, Grignolo M, Pegoraro A, Adinolfi E.   +4 more
europepmc   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source

What Is My Role? A Qualitative Study of Labor, Birth, and Postpartum Experiences of Partners. [PDF]

Nurs Health Sci
Pereda-Goikoetxea B, Fiaño-Santos M, Tomas-Riscado S, Uranga-Iturriotz M, Huitzi-Egilegor JX.   +4 more
europepmc   +1 more source