Results 81 to 90 of about 19,872,848 (346)

On the role of description

open access: yesJournal of Pure and Applied Algebra, 2001
The problem treated in this paper is connected with the possibility of an alternative axiomatization of the subobject classifier of a topos. It is proved that, if axiomatizing internal equality through a ``diagonal classifier'' (instead of the subobject classifier), and if an axiom asking for the existence of a ``description operator'', which enables ...
openaire   +2 more sources

Purification tags markedly affect self‐aggregation of CPEB3

open access: yesFEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito   +6 more
wiley   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

PERAN PEMERINTAH DAERAH DALAM PENGEMBANGAN OBYEK WISATA HUTAN BATU RAMMANG – RAMMANG DI KABUPATEN MAROS

open access: yesOtoritas: Jurnal Ilmu Pemerintahan, 2012
This study aims to determine the role of local governments in the development of forest tourism rammang rammang stone- Maros and determine the government's efforts in the development of tourism rammang-rammang stone forests Maros, using role government ...
Harnida Harnida, Muhammad Tahir
doaj  

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

open access: yesFEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao   +7 more
wiley   +1 more source

Sociophonetics: The Role of Words, the Role of Context, and the Role of Words in Context [PDF]

open access: yesTopics in Cognitive Science, 2018
AbstractThis paper synthesizes a wide range of literature from sociolinguistics and cognitive psychology, to argue for a central role for the “word” as a vehicle of language variation and change. Three crucially interlinked strands of research are reviewed—the role of context in associative learning, the word‐level storage of phonetic and contextual ...
openaire   +3 more sources

The Family Practitioner’s role in the integrated continuum of cancer care

open access: yesAfrican Journal of Primary Health Care & Family Medicine, 2015
No abstract ...
Martin de Villiers
doaj   +1 more source

Single‐cell insights into the role of T cells in B‐cell malignancies

open access: yesFEBS Letters, EarlyView.
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley   +1 more source

FRASA DAN KLAUSA DALAM KATA POLISINTESIS PADA BAHASA TOLAKI

open access: yesLingua: Jurnal Bahasa, Sastra dan Pengajarannya, 2017
This study examines the descriptions of phrases and sentences in the polysynthesis words.  Sources of data of this study polyshyntesis words in Tolaki Language.  Data were collected using observation and interview.
Ilfan Askul Pehala
doaj   +1 more source

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