Results 111 to 120 of about 1,344,519 (304)
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
The role of role theory in international political economy
This article demonstrates the benefits of using a role theory approach in the field of international political economy (IPE) by demonstrating its benefits relative to variants of the social constru...
Thies, Cameron, Wehner, Leslie
openaire +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
The purpose of this study was to explore the effect of a Gentle Tango dance programme (located in Victoria, Australia) on older adults’ close social relationships.
Raigan Francis, Russell Shuttleworth
doaj +1 more source
Long-term care professionals' views on pharmacists: a qualitative study using Role Theory. [PDF]
Gonçalves JR +4 more
europepmc +1 more source
Symmetry structure of special geometries
Using techniques from supergravity and dimensional reduction, we study the full isometry algebra of K\"ahler and quaternionic manifolds with special geometry.
Sub String Theory Cosmology and ElemPart +3 more
core +1 more source
The Foundational Role of Ergodic Theory [PDF]
The foundation of statistical mechanics and the explanation of the success of its methods rest on the fact that the theoretical values of physical quantities (phase averages) may be compared with the results of experimental measurements (infinite time averages).
openaire +2 more sources
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Family caregiving for Iranian men on methadone maintenance therapy according to role theory concept. [PDF]
Aghakhani N, Eghtedar S.
europepmc +1 more source
Theorizing about the service dominant logic: The bridging role of middle range theory
To date, the discourse about service dominant (S-D) logic has been largely theoretical, with the main focus on exploring the foundations for an integrating general theory of markets and marketing. Little attention has been given to the role of theorizing,
Brodie, Roderick J. +8 more
core +1 more source

