A fair accord : cradle to cradle as a design theory measured against John Rawls' Theory of justice and immanuel Kant's Categorical imperative [PDF]
, 2010 This essay explores a specific aspect of the role of attitude in design. The design of the built environment requires us constantly to make aesthetic and ethical judgments; every design decision has to be satisfactorily justified.
Voorthuis, J.C.T. +3 more
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CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Influence of Multi-Role Interactions in Community Group-Buying on Consumers' Lock-In Purchasing Intention From a Fixed Leader Based on Role Theory and Trust Transfer Theory. [PDF]
Front Psychol, 2022 Wu J, Chen Y, Pan H, Xu A.
europepmc +1 more source
Homotopy equivalent spectral transformation and Morse theory
, 1995 this paper is to establish systematic treatment of a speech-spectrum transformation and to make the notion of " deformation of spectral-surface". For this purpose, we use the algebraic topological language mainly developed in Morse theory.
Yoshinao Shiraki, Morse Theory
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Explaining small states’ changing patterns of peacekeeping contributions through role theory: the case of Austria and Belgium [PDF]
, 2018 This doctoral project explores the ways in which European small states’ approaches to peacekeeping have been affected by the changing nature of peace missions.
Gigleux, Victor Adolphe
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Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source
Molecular Oncology, EarlyView.EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain +10 more
wiley +1 more source
Theory-Oriented Software EngineeringI
, 2015 There has been a growing interest in the role of theory within Software Engineering (SE) research. For several decades, researchers within the SE research community have argued that, to become a ‘real ’ engineering science, SE needs to develop stronger ...
Stol, Klaas-Jan +5 more
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Molecular Oncology, EarlyView.We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
An empirical investigation of the utilitarian, social benefits in LBS information disclosure-The moderating effect of the gender based social role theory. [PDF]
Int J Inf Manage, 2021 Li Y, Mou J, Ye L, Long J, Huang WW.
europepmc +1 more source