Results 51 to 60 of about 6,570,416 (336)

Mapping the evolution of mitochondrial complex I through structural variation

FEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin, Tingting Chen, James A. Letts   +2 more
wiley   +1 more source

The Signaling Role of Promotions: Further Theory and Empirical Evidence [PDF]

, 2006
[Excerpt] An extensive theoretical literature has developed that investigates the role of promotions as a signal of worker ability. There have been no tests, however, of the empirical validity of this idea. In this paper we develop the theory in a manner
Jed Devaro, Jed Devaro, Michael Waldman, Michael Waldman   +3 more
core   +4 more sources

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

PERANAN WANITA MELAYU DALAM PROSES PENJAGAAN IBU BAPA TUA: DILEMA DAN CABARAN DALAM ERA GLOBALISASI (ROLES OF MALAY WOMEN IN THE PROCESS OF CARING FOR ELDERLY PARENTS: DILEMMA AND CHALLENGES IN THE ERA OF GLOBALISATION) [PDF]

Kajian Malaysia, 2010
Peningkatan bilangan warga tua (60 tahun ke atas) di beberapa negara Asia Tenggara termasuk Malaysia dan Indonesia semakin membimbangkan. Kepadatan penduduk warga tua di Malaysia dijangka akan meningkat kepada 2.2 juta orang pada tahun 2020.
Khadijah Alavi, Rahim M. Sail
doaj  

The Missing Professional Perspective: Medical, Veterinary, and Dual Degree Public Health Student Perceptions of One Health

Frontiers in Public Health, 2021
Introduction: One Health (OH) is an important concept to design appropriate public health responses to emerging diseases such as COVID-19. How trainee health professionals understand this concept is important to its implementation.
Rohini Roopnarine, Ellen Boeren, Julie-Anne Regan   +2 more
doaj   +1 more source

Axions: Theory and Cosmological Role [PDF]

Annual Review of Nuclear and Particle Science, 2013
We review recent developments in axion cosmology. Topics include axion cold dark matter, axions from topological defects, axion isocurvature perturbation and its non-Gaussianity, and axino/saxion cosmology in a supersymmetric axion model.
Kawasaki, Masahiro, Nakayama, Kazunori
openaire   +2 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Characteristic differences between award-winning and first-time blood donors in Guangzhou: a role theory perspective

Zhongguo shuxue zazhi
[Objective] To preliminarily develop a multidimensional blood donor role scale based on role theory and systematically compare the psychosocial characteristic differences between award-winning donors and first-time donors in Guangzhou, and to provide an ...
ZHU Yanxia, ZHENG Xiaoxiao, CHEN Jinyan, OUYANG Jian, LI Fengpei, HONG Xiaochun, HE Yanlin, XIE Guiyun   +7 more
doaj   +1 more source

How to share the process of graduate advising

FACETS, 2016
This paper starts a two-part series on graduate advising that integrates concepts from adult learning, leadership, and psychology into a conceptual framework for graduate advising.
H.H. Wagner, C. Boyd, R. Napper
doaj   +1 more source

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source