Results 81 to 90 of about 6,570,416 (336)

On the role of the chaotic velocity in relativistic kinetic theory

, 2013
In this paper we revisit the concept of chaotic velocity within the context of relativistic kinetic theory. Its importance as the key ingredient which allows to clearly distinguish convective and dissipative effects is discussed to some detail.
Garcia-Perciante, A. L., Moratto, Valdemar   +1 more
core   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Developing theoretical rigour in inter professional education [PDF]

, 2014
In this chapter, the author explores the meaning of theory and the role it plays in the development of interprofessional education. The chapter explores specifically the utility of the theory of social capital in the field and uses this as a case theory ...
Hean, Sarah
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

From organism to population: the role of life-history theory [PDF]

, 1994
The role of life-history theory in population and evolutionary analyses is outlined. In both cases general life histories can be analysed, but simpler life histories need fewer parameters for their description.
Sibly, R.M.
core  

Confinement and the center of the gauge group

, 2005
The question of the role of the center of the gauge group in the phenomenon of confinement in Yang-Mills theory is addressed. The investigation is performed from the most general perspective of considering all possible choices for the gauge symmetry ...
't Hooft, 't Hooft, Barresi, Bhanot, Cheluvaraja, Datta, de Forcrand, Dumitru, Dumitru, Fredenhagen, Greensite, Halliday, Holland, Holland, Holland, M. Pepe, Macfarlane, Mack, Mandelstam, Pepe, Svetitsky, Tomboulis   +21 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Lider-Üye Etkileşimine Çok Boyutlu Yaklaşım: Liden ve Maslyn’in Dört Boyutlu Lider-Üye Etkileşim Ölçeğinin Psikometrik Özelliklerine Yönelik Görgül Bir Araştırma

Akademik İncelemeler Dergisi, 2014
Lider-üye etkileşim teorisi ile ilgili erken dönem çalışmalarının çoğunda lider ile üyeler arasındaki ilişkiler tek boyutlu bir yaklaşımla ele alınmıştır.
Esin Cevrioğlu, Gültekin Yıldız, Hatice Özutku   +2 more
doaj  

Refining the Definition of Student Peer Feedback: The Role of Roles

Hermes
Refining the definition of student peer feedback in text production pedagogy and extending the definition to include the concept of peer-feedback roles, this article roots in higher education and explores definitions of peer feedback based on multiple ...
Carmen Heine, Anja Vesterager
doaj   +1 more source