Results 131 to 140 of about 11,777 (278)

Rolipram, a Selective Inhibitor of Phosphodiesterase Type 4, Pronouncedly Enhanced the Forskolin-Induced Promotion of Dopamine Biosynthesis in Primary Cultured Rat Mesencephalic Neurons.

, 1997
Nobuyuki Yamashita, Mio Miyashiro, Jun Baba, Aiko Sawa   +3 more
openalex   +2 more sources

Hyperlipidemia-induced cholesterol crystal production by endothelial cells promotes atherogenesis

Nature Communications, 2017
Atherosclerosis is characterized by subendothelial lipid retention believed to be the result of endothelial trancytosis. Here, the authors show that endothelium can take up and process LDL, generating cholesterol crystals that are deposited on the ...
Yvonne Baumer, Sara McCurdy, Tina M. Weatherby, Nehal N. Mehta, Stefan Halbherr, Pascal Halbherr, Noboru Yamazaki, William A. Boisvert   +7 more
doaj   +1 more source

Inhibition of Type 4 Phosphodiesterase by Rolipram and Ginkgo biloba Extract (EGb 761) Decreases Agonist-Induced Rises in Internal Calcium in Human Endothelial Cells [PDF]

, 2000
Manuel Campos‐Toimil, Claire Lugnier, Marié‐Thèrese Droy‐Lefaix, Kenneth Takeda   +3 more
openalex   +1 more source

Synergy between 5-HT4 receptor stimulation and phosphodiesterase 4 inhibition in facilitating acetylcholine release in human large intestinal circular muscle

, 2018
Background: Gastroprokinetic properties of 5-HT4 receptor agonists, such as prucalopride, are attributed to activation of 5-HT4 receptors on cholinergic nerves innervating smooth muscle in the gastrointestinal smooth muscle layer, increasing ...
Afzal, Alexander, Beavo, Bouras, Broad, Broad, Broad, Camilleri, Campbell-Dittmeyer, Cellek, Cellek, Chen, Craig, Elks, Emmanuel, Emmanuel, Galindo-Tovar, Galligan, Gershon, Hagiwara, Hidaka, Jones, Keating, Krobert, Leclere, Leclere, Lefebvre, Lefebvre, Loughney, Maeyer, Maeyer, Maeyer, Maurice, McLean, Michalski, Michie, O'Grady, Parker, Podzuweit, Priem, Priem, Priem, Prins, Prins, Rabe, Saeki, Sloots, Smith, Sudo, Tonini, Tralau-Stewart, Wan, Wang, Weninger, Yuan   +54 more
core   +1 more source

Involvement of cyclic AMP systems in morphine physical dependence in mice: prevention of development of morphine dependence by rolipram, a phosphodiesterase 4 inhibitor [PDF]

, 2001
Takayoshi Mamiya, Yukihiro Noda, Xiuhai Ren, Moustafa Mahmoud Hamdy, Shoei Furukawa, Tsutomu Kameyama, Kiyofumi Yamada, Toshitaka Nabeshima   +7 more
openalex   +1 more source

Rolipram inhibits leukocyte‐endothelial cell interactions in vivo through P‐ and E‐selectin downregulation [PDF]

, 2002
María‐Jesús Sanz, Ángeles Álvarez, Laura Piqueras, Miguel Jover Cerdá, Andrew C. Issekutz, Roy R. Lobb, Julio Cortijo, Esteban J. Morcillo   +7 more
openalex   +1 more source

Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro [PDF]

, 1994
Forssmann, W. G., Jonas, Udo, Meyer, M. F., Schulz-Knappe, P., Stief, Christian Georg, Taher, A., Truss, Michael C.   +6 more
core   +1 more source

The Phosphodiesterase Type 4 Inhibitor, Rolipram, Enhances Glucocorticoid Receptor Function [PDF]

, 2002
Amanda J. Miller
openalex   +1 more source

Development of a Catalytic Enantioselective Conjugate Addition of 1,3‐Dicarbonyl Compounds to Nitroalkenes for the Synthesis of Endothelin‐A Antagonist ABT‐546. Scope, Mechanism, and Further Application to the Synthesis of the Antidepressant Rolipram. [PDF]

, 2003
David M. Barnes, NULL AUTHOR_ID
openalex   +1 more source

Untargeted Metabolomic Profiling of Rolipram-Stimulated Immune Cells [PDF]

, 2016
Inflammation is a significant component of neurological diseases such as multiple sclerosis (MS). One potential anti-inflammatory agent, rolipram, was tested for efficacy in MS; however, despite showing promise in early trials, the drug has been largely ...
Shriber, Sterling, II
core   +1 more source