Results 201 to 210 of about 7,547 (235)
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Rolipram versus nortriptyline in gerontopsychiatric inpatients with major depression

Nordic Journal of Psychiatry, 1992
To define the therapeutic profile of the new putative antidepressant rolipram, a double-blind (double-dummy) study with 0.5 mg rolipram versus 25 mg nortriptyline three times daily was conducted in hospitalized gerontopsychiatric inpatients with major depression. During both therapies, improvement was achieved compared with base line. However, the rate
K. Behnke   +8 more
openaire   +1 more source

ROLIPRAM

Drugs of the Future, 1988
J. Crossland, J. Prous, J. Castañer
openaire   +1 more source

Synthesis of (±)-Rolipram

Synfacts, 2006
J.-I. Yoshida, K. Itami, K. Tonogaki
openaire   +1 more source

Rolipram promotes hippocampal regeneration in mice after trimethyltin-induced neurodegeneration

NeuroReport
This study aimed to investigate the effects of rolipram, a phosphodiesterase inhibitor, on brain tissue regeneration. Trimethyltin-injected mice, an animal model of hippocampal tissue regeneration, was created by a single injection of trimethyltin chloride (2.2 mg/kg, intraperitoneally).
Masashi, Sakurai   +3 more
openaire   +2 more sources

[Rolipram reversed salbutamol tolerance in guinea pig trachea].

Yao xue xue bao = Acta pharmaceutica Sinica, 2001
Studies were carried out to examine the role of phosphodiesterase(PDE) III and PDE IV in the development of tachyphylaxis of isolated guinea pig trachea to beta 2 adrenoceptor agonists. Treating trachea with salbutamol(SB) 1 mumol.L-1 for 1 h produced a 5-fold rightward shift of the SB concentration-response curve for the spasmolytic effect against ...
J Q, Chen, Y B, Lu, H L, Zhou
openaire   +1 more source

Synthesis and evaluation of clioquinol-rolipram/roflumilast hybrids as multitarget-directed ligands for the treatment of Alzheimer's disease.

European journal of medicinal chemistry, 2019
Jinhui Hu   +5 more
semanticscholar   +1 more source

Attenuation of ethanol abstinence-induced anxiety- and depressive-like behavior by the phosphodiesterase-4 inhibitor rolipram in rodents

Psychopharmacology, 2017
Mei-Fang Gong   +8 more
semanticscholar   +1 more source

Rolipram Attenuates Early Brain Injury Following Experimental Subarachnoid Hemorrhage in Rats: Possibly via Regulating the SIRT1/NF-κB Pathway

Neurochemical Research, 2018
Yucong Peng   +8 more
semanticscholar   +1 more source

Rolipram

2010
Stan Floresco   +116 more
openaire   +1 more source

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