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Multistep continuous-flow synthesis of (R)- and (S)-rolipram using heterogeneous catalysts
Nature, 2015T. Tsubogo, H. Oyamada, S. Kobayashi
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Inhibition of uterine contractions by rolipram in vitro.
Arzneimittel-Forschung, 1989The human myometrium contains two different forms of phosphodiesterase (PDE). One form is characterized by its lack of substrate specificity and its calcium-calmodulin dependence. The other one is selective for cyclic adenosine monophosphate (cAMP).
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Journal of labelled compounds & radiopharmaceuticals, 2016
D. Thomae +8 more
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D. Thomae +8 more
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