Results 61 to 70 of about 792,170 (211)

Rosemary metabolite carnosic acid opens Kv1.1 via its voltage sensor and corrects Kv1.1‐linked episodic ataxia in mice

British Journal of Pharmacology, EarlyView.
Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville, Ryan F. Yoshimura, Hanh A. Nguyen, Ruiming Zhao, Derk J. Hogenkamp, Steve A. N. Goldstein, Geoffrey W. Abbott   +6 more
wiley   +1 more source

Historical, Geometrical, and Constructive Analyses of the Rotonda Roman Baths in Catania (Sicily)

Buildings
One of the main icons of the Roman civilisation are thermal baths, built as public places for personal hygiene, body and mind relaxation, recreation, social encounters, and sport.
Carola Tardo, Laura Floriano, Mariangela Liuzzo, Anna Maria Gueli, Giuseppe Stella, Giuseppe Margani   +5 more
doaj   +1 more source

Conclusions. Le nouvel essor des recherches archéologiques à Baelo au xxie siècle

Mélanges de la Casa de Velázquez, 2017
The archaeological research carried out at Bolonia (Tarifa, Cádiz) from 1917 to 1921 and from 1964 to 1990 focused almost exclusively on the remains of the Hispano-Roman town.
Pierre Sillières
doaj   +1 more source

Defrosting humanism: Losing my ethical worldview in the wake of October 7th and Israel's retaliation

Ethos, EarlyView.
Abstract This auto‐ethnographic analysis describes the loss of my ethical worldview and my attempts to regain it following the October 7th Hamas attack on Israel and the subsequent Israeli retaliation. On October 7th, I was unable to feel compassion for the people of Gaza or to take action against the Israeli retaliation, aspects that I used to see as ...
Yael Assor
wiley   +1 more source

Meeting the New (Old) Ecological Challenges for Art Education

International Journal of Art &Design Education, EarlyView.
Abstract The discussion examines the emerging ecological critique of art education, which frames artistic production, especially in the plastic arts, as environmentally unsustainable due to its reliance on non‐essential material consumption. I argue that this critique, while contemporary in form, echoes long‐standing philosophical concerns, beginning ...
Dorit Barchana‐Lorand
wiley   +1 more source

The Mosaic that Never Was. Tesserae and Raw Material for an Unlaid Mosaic Floor in Trimithis (Dakhla Oasis, Egypt)

Journal of Mosaic Research, 2020
In 2012, the international team of the archaeological expedition at Amheida, under the primary sponsorship of the Institute for the Study of the Ancient World (ISAW, New York University), found a large amount of pristine mosaic tesserae in the Roman ...
Marina M. S. NUOVO, Silvia PRELL
doaj   +1 more source

Ultra‐High‐Speed Sintering of 3.5Y‐TZP Zirconia: Time Reduction Without Compromising Translucency

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To assess, firstly, the impact of three sintering speeds on translucency and grain size of 3.5Y‐TZP zirconia (Katana HT) across clinically relevant thicknesses, and secondly, the effect of thermocycling on translucency. Materials and Methods Disc specimens were fabricated at six thicknesses (0.7–2.0 mm) and sintered using SLOW (7 h),
Tatiana Roman, Hamdi Jmal, Teissir Ben Ammar , Adrien Greffet, Marc Lenertz, Olivier Etienne   +5 more
wiley   +1 more source

Physicochemical and metagenomic analysis of samples from the Roman Baths (Bath, UK) reveals high bacterial and archaeal diversity and a potential for antimicrobial discovery

The Microbe
Antimicrobial resistance of pathogenic bacteria to currently used antibiotics killed an estimated 1.27 million people in 2019 and it is believed that this toll will increase to 10 million per year by 2050.
Enus Fina, Michele Kiernan, Bonnie Whatmough, Nathaniel J. Clark, Jazmin Conway, Iga W. Wieczorek, Laura Carey, Zofia Matyjaszkiewicz, Philip J. Warburton, Mathew Upton, Lee P. Hutt   +10 more
doaj   +1 more source

Fish welfare in a changing world: New developments and current challenges

Journal of Fish Biology, EarlyView.
Abstract The welfare of non‐human animals is central to ethical discussions on animal use, with increasing attention to fish welfare across research, aquaria, aquaculture, and fisheries. This paper reviews current theoretical approaches to animal welfare and recent advances in defining and assessing fish welfare since the seminal paper by Huntingford ...
Sonia Rey Planellas, João L. Saraiva, Eliane Gonçalves‐de‐Freitas, Pablo Arechavala‐Lopez, Bernice Bovenkerk, Michael Breen, Steven J. Cooke, Martin Føre, Lene Northwood, Lars Helge Stien, Sunil Kadri, Chris Noble, Jonatan Nilsson, Fernando Rodriguez, Cosme Salas, Peter Sandøe, Hans van de Vis   +16 more
wiley   +1 more source

Considering New Functions in Thermal Bath Buildings: The Singular Heating Water System from the Roman Spa of Termas de São Vicente (Penafiel, Portugal)

Zephyrus
The archaeological research we carried out between 2020-2023 (pipa bal-saovicente) in the Roman Spa of Termas de São Vicente, in Penafiel, Portugal, in order obtain a better understanding of this archaeological site preserved in the park of the modern ...
Silvia González Soutelo, Juan Diego Carmona Barrero, Teresa Soeiro, Inmaculada Donate Carretero, Clara Seara Erwelein   +4 more
doaj   +1 more source