Results 181 to 190 of about 26,417 (254)
British Journal of Pharmacology, EarlyView.Background and Purpose Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder caused primarily by loss‐of‐function mutations in the voltage‐gated potassium channel Kv1.1 (KCNA1). Small molecules that restore Kv1.1 activity hold promise as targeted therapies for EA1, yet current pharmacological strategies remain limited ...
Rían W. Manville +6 more
wiley +1 more source
The geography of economic mobility in 19th‐century Canada
Canadian Journal of Economics/Revue canadienne d'économique, EarlyView.Abstract This paper uses linked Census records from 1871 to 1901 to compute intergenerational mobility for Canadian regions and census divisions. The results reveal sharp differences in mobility over space: Ontario featured high relative and absolute mobility, Quebec low relative and absolute mobility and the Maritimes low absolute mobility.
Luiza Antonie +3 more
wiley +1 more source
Child &Family Social Work, EarlyView.ABSTRACT Understanding social factors that affected how people interpreted the meanings of COVID‐19 measures is important in postpandemic times. This study applies perspectives from research on emotions as one of the possible explanations and focuses on how institutions and their measures are perceived in the context of individual emotional situations.
Eva M. Hejzlarová
wiley +1 more source
Child &Family Social Work, EarlyView.ABSTRACT Establishing permanence for young people growing up in care is widely recognized as central to promoting stability and positive outcomes. Historically, permanence has been understood primarily as a legal status; however, contemporary scholarship increasingly emphasizes relational permanence, highlighting the importance of enduring, supportive ...
Sinead Whiting
wiley +1 more source
Gender inequality in urban British Africa: Evidence from Anglican marriage registers
The Economic History Review, EarlyView.Abstract We examine the colonial origins and evolution of gender inequality in mission schooling and formal labour force participation across six cities in British colonial Africa, using marriage register data for some 30,000 Anglican brides and grooms well‐positioned to benefit from colonial educational and employment opportunities.
Felix Meier zu Selhausen, Jacob Weisdorf
wiley +1 more source
The depth and breadth of capitalism at the Cape
The Economic History Review, EarlyView.Abstract Limited liability company legislation was introduced to the Cape Colony in 1861. An amendment in 1892 led to wider adoption, expanding and diversifying the capital market. Using novel data from the Cape Joint Stock Archive between 1892 and 1902, this paper examines who invested, where capital flowed, and how these patterns shaped firm outcomes
Edward Kerby, Lloyd Melusi Maphosa
wiley +1 more source
The Economic History Review, EarlyView.Abstract To persuade creditors to lend, cities in the Low Countries relied on a community responsibility system that made all citizens personally liable for public debt. This exposed itinerant citizens to significant risks: their merchandise could be confiscated by creditors, and they could even be imprisoned for debt.
Jaco Zuijderduijn
wiley +1 more source
Evaluation of a Google Classroom Biochemistry Course for Undergraduate Dentistry Students
European Journal of Dental Education, EarlyView.ABSTRACT Introduction Instructing students for biochemistry courses is consistently a challenge. It is important to employ various didactic strategies to improve understanding of the chemical processes that occur in living organisms and to identify basic tools for experimental teaching.
Marisol Rosas‐Martínez +4 more
wiley +1 more source
European Journal of Philosophy, EarlyView.Abstract It is often said that dignity is the ground of human rights. But what grounds dignity? According to proponents of the metaphysical view, dignity is grounded in our rational capacities, our sense of justice, or a disjunctive list of valuable capacities.
Jordan David Thomas Walters
wiley +1 more source
Retrieving Your Concepts: Iris Murdoch on Original Sin
European Journal of Philosophy, EarlyView.Abstract In The Sovereignty of Good, Iris Murdoch argues that our moral thinking will be impoverished until it possesses a secular conception of original sin. Such a notion would need to remove unacceptable Christian baggage while retaining a genuine claim to be a descendant of the original Christian concept.
Samuel Filby
wiley +1 more source