Results 41 to 50 of about 500 (140)

Real‐world prevalence of PD‐L1 positivity in early‐stage/metastatic triple‐negative breast cancer: primary results and pathology insights from the global retrospective observational VANESSA study

Histopathology, Volume 88, Issue 7, Page 1373-1384, June 2026.
In the real‐world VANESSA study in triple‐negative breast cancer, PD‐L1‐positive prevalence was 38% in early‐stage and 20% in metastatic tumours, lower than in prospective trials. The lower prevalence in smaller versus larger tissue samples and by local versus central assessment underlines the importance of robust PD‐L1 testing to determine eligibility
Corrado D'Arrigo, Sitki Tuzlali, Romualdo Barroso‐Sousa, Nagi S El Saghir, Rebecca Dent, Nataša Medić‐Milijić, Gyungyub Gong, Shahin Sayed, Tu Thai Anh, Alisan Zirtiloglu, Götz Hartleben, Paula Toro, Iman Estaytieh, Enya Weber, Regula Deurloo, João Mouta, Lazar Popovic   +16 more
wiley   +1 more source

Landscape features predict broad‐scale seed rain patterns across fragments of the Brazilian Atlantic Forest

Journal of Ecology, Volume 114, Issue 5, May 2026.
Along with precipitation, forest cover emerges as a fundamental driver of alpha and beta diversity in the seed rain. This highlights the role of habitat amount at the landscape level over patch‐level features, like patch size, for seed dispersal. However, increased seed density can be related to higher dispersal rates in forest borders.
Luís Felipe Daibes, Haldre S. Rogers, Fulbert J. K. Gnonlonfoun, Talita Zupo, Rafael Barbizan Sühs, Daniella Vinha, Débora Cristina Rother, Paulo Alves Almeida Junior, Angela Luciana de Avila, José Marcos Barbosa, Romualdo Morelatto Begnini, Antonio Jorge Tourinho Braga, Marcos Vinicius Wincker Caldeira, Elivane Salete Capellesso, Andre Targa Cavassani, Eliana Cazetta, Ricardo Gomes Cesar, Marilena Menezes Silva Conde, Cléber Covre, Henrique Machado Dias, Pavel Dodonov, Rinaldo Luiz Caraciolo Ferreira, Cintia Gomes Freitas, Milena Gama, Gerhard Gottsberger, Flavia Moraes de Jesus, Carlos Alfredo Joly, Ute Christiane Knörr, Sustanis Horn Kunz, Vinícius Londe, Ana Lícia Patriota Feliciano Marangon, Luiz Carlos Marangon, Fabiana Maraschin‐Silva, Marcia C. M. Marques, Adriana Maria Zanforlin Martini, Valéria Forni Martins, Larissa Lopes Mellinger, Luís Fernando Tavares de Menezes, Sandra Bos Mikich, Luiz Fernando Duarte de Moraes, Marcelo Trindade Nascimento, Marcelo Augusto Meratti de Oliveira, Monique Perini, Julia Fleming Pimentel, Daniel Piotto, Rita de Cássia Quitete Portela, Janaine Isabela da Silva Rocha, Ricardo Ribeiro Rodrigues, Jerônimo Boelsums Barreto Sansevero, Amanda Souza dos Santos, Flavio Antonio Maës dos Santos, Jaqueline Pêgo Quintino Santos, Nelson Augusto Santos Junior, Tanise Luisa Sausen, Carlos Rodrigues da Silva, Joselane Príscila Gomes da Silva, Jorge Yoshio Tamashiro, Luiz Roberto Zamith, Leticia Bolian Zimback, Raquel Fernandes Zorzanelli, Victor Pereira Zwiener, Renato Augusto Ferreira de Lima, Luís Fábio Silveira, Marco Aurélio Pizo   +63 more
wiley   +1 more source

The Binding of 3‐O‐Methylfluorescein Phosphate to the Catalytic Domain of the Human CDC25B Phosphatase: A Structural Investigation

ChemBioChem, Volume 27, Issue 7, 14 April 2026.
Structural studies on the complex that CDC25B C473S (CDC25B‐S) forms with the 3‐O‐methylfluorescein phosphate (3‐OMFP) reveal how the fluorogenic substrate binds CDC25B‐S, engaging key binding regions and inducing structural adjustments that stabilize the protein.
Romualdo Troisi, Rosario Rullo, Valeria Napolitano, Grzegorz M. Popowicz, Emmanuele De Vendittis, Filomena Sica   +5 more
wiley   +1 more source

Guided Cavity Preparation to Access an Invagination and Preserve Pulp Vitality of an Immature Maxillary Lateral Incisor With Type IIIa Dens Invaginatus: Technical Overview and a Case Report With 3‐Year Follow‐Up

International Endodontic Journal, Volume 59, Issue 4, Page 737-743, April 2026.
ABSTRACT Aim Dens invaginatus (DI) is a developmental anomaly often associated with caries and periapical pathosis. This report describes guided access and filling of an infected invagination in a maxillary lateral (tooth #22) with long‐term preservation of pulp vitality.
Francesc Abella Sans, Venkateshbabu Nagendrababu, Nandini Suresh, Marc Garcia‐Font, Paul M. H. Dummer   +4 more
wiley   +1 more source

Flavouring Group Evaluation 82 Revision 2 (FGE.82Rev2): Consideration of epoxides evaluated by JECFA

EFSA Journal, Volume 24, Issue 4, April 2026.
Abstract The Panel on Food Additives and Flavourings (FAF) of the European Food Safety Authority was requested to consider evaluations of flavouring substances assessed since 2000 by the Joint FAO/WHO Expert Committee on Food Additives (JECFA), and to decide whether further evaluation is necessary, as laid down in Commission Regulation (EC) No.
EFSA Panel on Food Additives and Flavourings (FAF), Laurence Castle, Monica Andreassen, Gabriele Aquilina, Maria Bastos, Polly Boon, Biagio Fallico, Rex FitzGerald, María José Frutos Fernández, Bettina Grasl‐Kraupp, Ursula Gundert‐Remy, Rainer Gürtler, Eric Houdeau, Marcin Kurek, Henriqueta Louro, Patricia Morales, Sabina Passamonti, Gisela Degen, Karl‐Heinz Engel, Maria Carfí, Ana Criado, Borana Dino, Carla Martino   +22 more
wiley   +1 more source

An enigmatic tropical conifer from the Early Cretaceous of Gondwana [PDF]

Acta Palaeontologica Polonica
We describe a new genus of Leliacladus Batista & L.Kunzmann with the type species Leliacladus (Brachyphyllum) castilhoi (Duarte, 1985) Batista & L.Kunzmann gen. nov. et comb.
Maria Edenilce P. Batista, Antônio Álamo F. Saraiva, Flaviana J. De Lima, Renan A.M. Bantim, Allysson P. Pinheiro, Daniel B. Silva, Lutz Kunzmann   +6 more
doaj   +1 more source

From Barns to Bushes: Exploring the ECOFF‐Based Non‐Wild‐Type Status of Campylobacter spp. in Pets, Livestock, Synanthropic Birds and Wild Animals in Northwestern Italy

Zoonoses and Public Health, Volume 73, Issue 1, Page 30-44, February 2026.
ABSTRACT Introduction Antimicrobial resistance (AMR) poses a significant threat to both humans and animals. Zoonotic bacteria, such as Campylobacter, contribute to human infections and the spread of AMR, particularly through livestock, pets and wildlife. We investigated the prevalence, distribution and EUCAST ECOFF‐based wild‐type (WT) vs.
Aitor Garcia‐Vozmediano, Barbara Moroni, Cristina Marra, Monica Pitti, Giuliano Garofolo, Francesca Marotta, Roberta Di Romualdo, Simona Zoppi, Giuseppe Ru   +8 more
wiley   +1 more source

Analysis of a Cretaceous (late Aptian) high-stress ecosystem: The Romualdo Formation of the Araripe Basin, northeastern Brazil

Cretaceous Research, 2019
Abstract The Cretaceous (upper Aptian) Romualdo Formation of the Araripe Basin, northeastern Brazil, is a marine-influenced, predominantly fine-grained siliciclastic unit. In the eastern part of the basin, it corresponds to a depositional sequence composed of two transgressive-regressive cycles.
Franz T. Fürsich, Michele Andriolli Custódio, Suzana A. Matos, Manja Hethke, Fernanda Quaglio, Lucas Veríssimo Warren, Mario L. Assine, Marcello G. Simões   +7 more
openaire   +2 more sources

INTEGRAL EDUCATION ON SCHEDULE: "A FULL-TIME SCHOOL OR THAT AIMS AN INTEGRAL FORMATION, IS A POSSIBILITY FOR THE IMPROVEMENT OF TEACHING IN BRAZIL". AN INTERVIEW WITH ROMUALDO PORTELA DE OLIVEIRA

Educação: Teoria e Prática, 2018
Integral education has been the focus of policy discussions in diverse segments within the context of Brazilian education, with special emphasis on academic productions that consider the fruitful dialogue between public policies and educational ...
Camila Arelaro Caetano
doaj   +1 more source

Morphology and paleoecology of a hybodontiform with serrated teeth, Priohybodus arambourgi, from the Late Jurassic of northeastern Brazil

The Anatomical Record, Volume 309, Issue 1, Page 5-32, January 2026.
Abstract Hybodontiformes was a diverse, successful, and important group of shark‐like chondrichthyans known from a variety of ecosystems. Some representatives of the order had a wide palaeogeographic distribution, as is the case with Priohybodus arambourgi. With a multicuspidate crown, P. arambourgi was the first hybodontiform to develop fully serrated
Estevan Eltink, Kelly Roberta da Silva, Marco Aurélio Gallo de França, Débora Melo Ferrer de Morais, Matías Soto, Christopher J. Duffin   +5 more
wiley   +1 more source