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Evidence of Iron Accumulation in Cerebral Adrenoleukodystrophy: A Potential Novel Disease Mechanism

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT In this first application of Quantitative Susceptibility Mapping Source Separation to cerebral adrenoleukodystrophy, we uncovered alterations in iron and myelin within lesions and normal appearing white matter. As validation, we demonstrate abnormal iron accumulation in those same compartments within primary brain tissue.
Christina L. Nemeth +8 more
wiley +1 more source

Assessing Corvus frugilegus (Rook) habitat preferences through flock-size-specific species distribution modeling using citizen science data

Global Ecology and Conservation
Urban environments face significant challenges due to the presence of large bird flocks, such as rooks (Corvus frugilegus), which contribute to sanitation issues and property damage.
Jiweon Yun, Seunghyeon Lee, Youngkeun Song +2 more
doaj +1 more source

Relationship Between Neurologic Symptoms and Signs and FMR1 Genotype in Premutation Carriers

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) is the most severe late‐onset condition caused by a premutation in the FMR1 gene, characterized by expanded CGG triplet repeats of 55–200. Clinical presentations of FXTAS, including gait ataxia, kinetic tremor, cognitive decline, and rare Parkinsonism, are linked to ...
Flora Tassone +8 more
wiley +1 more source

Notes on simplicial rook graphs [PDF]

, 2014
The simplicial rook graph ${\rm SR}(m,n)$ is the graph of which the vertices are the sequences of nonnegative integers of length $m$ summing to $n$, where two such sequences are adjacent when they differ in precisely two places.
Brouwer, Andries E. +3 more
core +1 more source

Fast Fourier Transforms for the Rook Monoid

, 2007
We define the notion of the Fourier transform for the rook monoid (also called the symmetric inverse semigroup) and provide two efficient divide-and-conquer algorithms (fast Fourier transforms, or FFTs) for computing it.
Malandro, Martin, Rockmore, Daniel N.
core +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit +11 more
wiley +1 more source

The old friends hypothesis: evolution, immunoregulation and essential microbial inputs

Frontiers in Allergy, 2023
In wealthy urbanised societies there have been striking increases in chronic inflammatory disorders such as allergies, autoimmunity and inflammatory bowel diseases. There has also been an increase in the prevalence of individuals with systemically raised
Graham A. W. Rook
doaj +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

Arthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby +448 more
wiley +1 more source

Two Vignettes On Full Rook Placements [PDF]

, 2013
Using bijections between pattern-avoiding permutations and certain full rook placements on Ferrers boards, we give short proofs of two enumerative results.
Bloom, Jonathan, Vatter, Vince
core

NanoMOF‐Based Multilevel Anti‐Counterfeiting by a Combination of Visible and Invisible Photoluminescence and Conductivity

Advanced Functional Materials, EarlyView.
This study presents novel anti‐counterfeiting tags with multilevel security features that utilize additional disguise features. They combine luminescent nanosized Ln‐MOFs with conductive polymers to multifunctional mixed‐matrix membranes and powder composites. The materials exhibit visible/NIR emission and matrix‐based conductivity even as black bodies.
Moritz Maxeiner +9 more
wiley +1 more source

discrete mathematics and combinatorics
theoretical computer science
exact enumeration problems, generating functions

mathematics
computational theory and mathematics
combinatorial identities, bijective combinatorics

rook placement
simplicial rook graph
laplacian matrix