Results 71 to 80 of about 30,905 (302)

Hamilton Parents Centre 1957-2003: A sociological history [PDF]

open access: yes, 2004
This is a "sociological history" of Hamilton Parents Centre and as such presents the stories' of Hamilton Parents Centre organised both chronologically and thematically.
Morgans, Blair   +2 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

Risk factors and prevalence of newborn hearing loss in a private health care system of Porto Velho, Northern Brazil

open access: yesRevista Paulista de Pediatria, 2013
OBJECTIVE: To determine the prevalence of hearing loss and to analyze the results of newborn hearing screening and audiological diagnosis in private health care systems.
Juliana Santos de Oliveira   +3 more
doaj   +1 more source

Impact of Immigrant Entrepreneurs and Workers in Leisure and Hospitality Businesses: Massachusetts and New England [PDF]

open access: yes, 2010
This report examines the role and impact of immigrant entrepreneurs and workers on Leisure and Hospitality businesses in New England, particularly Massachusetts. A significant portion of state economies in New England, especially in Massachusetts, relies
C. Eduardo Siqueira   +5 more
core  

Air Ventilation in Tuberculosis Patient Care Room in Sidoarjo Regional Hospital

open access: yes, 2023
Tuberculosis or frequently known as TB is a lung disease caused by Mycobacterium Tuberculosis bacteria colonies, this disease is transmitted through the air when a tuberculosis sufferer sneezes, coughs, spits, or even talks, where the air containing the bacteria is inhaled by another person Today Tuberculosis is categorized as a deadly disease for ...
Pahlevi, Mohammad Irvan Reza   +2 more
openaire   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Breastfeeding education: where are we going? A systematic review article [PDF]

open access: yes, 2016
Background: UNICEF (United Nations International Children’s Emergency Fund) and WHO estimate that if all babies were breastfed for at least the first six months of their lives, the rate of morbidity and malnutrition would sig-nificantly decrease all over
Ban Frangež, Helena   +7 more
core  

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Use of Standardized Patient Scenarios to Train Medical Assistants in an Ambulatory Rehabilitation Medicine Clinic [PDF]

open access: yes, 2017
Objectives: To improve the efficiency of our outpatient Rehabilitation Medicine clinic without sacrificing high value/quality patient care. To clarify the responsibilities of the MA and identify areas of redundancy in the rooming process.
Asprec, MD, Lawrence   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

open access: yesMolecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh   +12 more
wiley   +1 more source

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