Results 231 to 240 of about 295,445 (314)

Resilient gut microbiome is linked to immune control in HIV-1 infection. [PDF]

Biol Direct
Silva JMM, Azevedo JLLC, Bezerra KG, Guilarde AO, Souza LCS, Guimarães RF, Leite P, Júnior HM, Gardinassi LG, Romão PRT, Fonseca SG.   +10 more
europepmc   +1 more source

Modulating Purothionin Accumulation and Signal Peptide Cleavage Fine‐Tunes Wheat Flour Gluten Properties to Improve Cookie‐Making Quality

Advanced Science, EarlyView.
Dual genetic strategies for improving wheat processing quality by regulating purothionin accumulation to modulate gluten quantity and quality. The first strategy involves targeting signal peptide (SP) cleavage sites (e.g., through mutation) to indirectly reduce gluten content, thereby disrupting gluten network formation.
Yijie Liu, Siyuan Chang, Zhaoheng Zhang, Tianqi Kang, Mingde Liu, Yuan Zong, Fei Ni, Yinguang Bao, Ruijie Zhang, Xiaobang Zhang, Jinkun Du, Mingming Xin, Zhaorong Hu, Jie Liu, Zhongfu Ni, Qixin Sun, Yingyin Yao   +16 more
wiley   +1 more source

Natural-history traits suspected behind interspecific variations of bark- and wood-boring beetles in response to trap size and design. [PDF]

Sci Rep
Caiti E, Hasbroucq S, Grégoire JC.
europepmc   +1 more source

Berry Brook Watershed Management Plan –Implementation Projects Phase III [PDF]

, 2017
The City of Dover, University of New Hampshire Stormwater Center (UNHSC)   +1 more
core   +2 more sources

PBRM1 Deficiency Reshapes an Immune Suppressive Microenvironment Through Epigenetic Tuning of PBRM1‐KDM5C‐IL6 Axis in ccRCC

Advanced Science, EarlyView.
PBRM1 ranks as the second most commonly mutated gene in ccRCC. This study reveals that PBRM1 loss promotes an immunosuppressive microenvironment by elevating M2 TAMs via the KDM5C–IL‐6 axis. These M2 TAMs, along with CAFs, form a barrier that excludes CD8+ T cells. Targeting IL‐6 synergizes with anti‐PD1 therapy, offering a promising strategy for PBRM1‐
Wenjiao Xia, Hongru Wang, Yu Dong, Zitong Yang, Yiyang Zhou, Zhinan Xia, Qinchen Li, Liangliang Ren, Yichun Zheng, Junliang Yan, Dongmei Ma, Zhi Chen, Xingang Cui, Guixin Zhu, Cheng Zhang   +14 more
wiley   +1 more source

Mandibular Distraction Osteogenesis Guided by 3D Model and Monitored with Ultrasonography: A Case Report. [PDF]

Pediatr Rep
Hocková B, Issa J, Malček M, Dowgierd K, Slávik R, Cheng YC, Králinský K, Stebel A.   +7 more
europepmc   +1 more source

Diffusion‐MRI‐Based Estimation of Cortical Architecture via Machine Learning (DECAM) in Primate Brains

Advanced Science, EarlyView.
We present Diffusion‐MRI‐based Estimation of Cortical Architecture via Machine Learning (DECAM), a deep‐learning framework for estimating primate brain cortical architecture optimized with best response constraint and cortical label vectors. Trained using macaque brain high‐resolution multi‐shell dMRI and histology data, DECAM generates high‐fidelity ...
Tianjia Zhu, Minhui Ouyang, Shufang Tan, Jianlin Guo, Ziqin Zhang, Xuan Liu, Risheng Liu, Hao Huang   +7 more
wiley   +1 more source

Toward functional and structurally complex Frank-Kasper phases via creating concavities on supramolecular micelles. [PDF]

Chem Sci
Wang YR, Weng JH, Huang SJ, Su CJ, Jeng US, Chang PY, Chuang WT, Wang CL.   +7 more
europepmc   +1 more source

Hepatocyte Mettl3 Deficiency Drives Primary Sclerosing Cholangitis and Liver Fibrosis via Cholangiocyte‐Macrophage Crosstalk

Advanced Science, EarlyView.
Schematic illustration demonstrating that hepatic Mettl3 depletion significantly elevates the secretion of Mif and Csf1. This elevation facilitates Trem2+ macrophage infiltration and triggers cholangiocyte remodeling through the Spp1‐Cd44 interaction, resulting in spontaneous PSC development in vivo.
Wenting Pan, Yuting Yong, Yuanshuai Li, Gaona Shi, Min Zhang, Lingfei Wan, Yue Zhao, Wenling Zhan, Yanli Lin, Qiaozhen Qin, Xupeng Chen, Yanli Ni, Haixu Chen, Wenzai Shi, Xiaomeng Guo, Juan Chen, Shuchen Liu, Youliang Wang, Bing Liu, Xinlong Yan   +19 more
wiley   +1 more source

Simultaneous Reconstruction of Medial Patellofemoral and Medial Patellotibial Ligaments. [PDF]

Video J Sports Med
Martinez-Cano JP, Cuadros JA, Gravini G, Mejia FM.   +3 more
europepmc   +1 more source