Results 211 to 220 of about 298,662 (304)

HNRNPD Induces Radioresistance in Nasopharyngeal Carcinoma by Sequestering GRAMD4 mRNA in Stress Granules

Advanced Science, EarlyView.
HNRNPD promotes radioresistance in nasopharyngeal carcinoma by enhancing stress granule assembly and sequestering GRAMD4 mRNA. This suppresses GRAMD4 translation and inhibits mitochondrial apoptosis. Targeting the integrated stress response with ISRIB restores GRAMD4 expression and sensitizes tumors to radiotherapy, revealing a translational control ...
Yingzi Li, Tong Xiang, Yuanyuan Liu, Desheng Weng, Jingjing Zhao, Hao Chen, Yan Tang, Songzuo Xie, Hao Zhang, Jun Luo, Xinyi Yang, Qiuzhong Pan, Muping Di, Jianchuan Xia   +13 more
wiley   +1 more source

From Efficacy to Effectiveness: When Proven Therapies Fail. [PDF]

Circ Popul Health Outcomes
McClintick D, Cheng S, Ebinger JE.
europepmc   +1 more source

Newsroom: NLJ: Goldstein on Tea Party [PDF]

, 2012
Roger Williams University School of Law
core   +1 more source

Liquid Metal Nanotransformers for Drug‐Resistant Pan‐Cancer Therapy in Patient‐Derived Organoids

Advanced Science, EarlyView.
Pan‐cancer therapies are severely limited in drug‐resistance patients due to genetic mutations and other factors, resulting in poor therapeutic outcomes and constrained clinical benefit. Liquid metal nanotransformers, a new class of shape‐transformable nanomaterials capable of dramatic morphological changes, offer a promising physical strategy to ...
Xiaojie Yuan, Xuelin Wang, Zhongyao Chen, Shuo Wang, Weining Gao, Ziyi Chen, Runyang Li, Cheng Hao, Lei Zhang, Qiongqiong Zhang, Ke Zhang, Mei Yu, Qian Liu, Jingxuan Wang, Huiping Li, Simpkins Fiona, Jing Liu, Qiang Liu, Peng Liu, Yawei Hu   +19 more
wiley   +1 more source

Diagnosis of Plasmodium falciparum malaria at very low parasitaemias using a commercially available LAMP assay and RDT. [PDF]

Trans R Soc Trop Med Hyg
Payne RO, Edwards NJ, Themistocleous Y, Silk SE, Barrett JR, Rawlinson TA, Lim IW, Draper SJ, Minassian AM.   +8 more
europepmc   +1 more source

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Photoprotective Properties of Extracts Derived from <i>Neoglaziovia variegata</i> (Arruda) Mez Incorporated into Mesoporous TiO₂. [PDF]

ACS Omega
Miranda FAA, Oliveira VV, Bezerra RDS, Osajima JA, Silva-Filho EC.   +4 more
europepmc   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source

Complete genome sequences of Cluster FE <i>Arthrobacter globiformis</i> phages Piku and Utopia. [PDF]

MicroPubl Biol
Labib S, Hafeez A, Choudry H, Ali R, Hussain K, Olascoaga E, Khan M, Kamal Y, Fatima S, Slakeski N, Syeda M, Muhammad I, Khan B, Pérez Morales T.   +13 more
europepmc   +1 more source

Something Wicked this Way Comes: Constitutional Transformation and the Growing Power of the Supreme Court [PDF]

, 2002
Stein, Matthew B.
core   +1 more source