Results 191 to 200 of about 83,746 (304)

TPI1 Loss Triggers a Metabolite‐Driven Mitochondrial Redox Vulnerability via the SARM1–cADPR–Ca2+ Axis

Advanced Science, EarlyView.
Metabolite‐driven redox stress governs cancer cell senescence. TPI1 deficiency elevates DHAP, initiating SARM1‐dependent cADPR‐Ca2+ release. Mitochondrial ROS surge subsequently induces DNA damage and senescence, offering a conserved therapeutic target in multiple cancers.
Chunyu Liu, Shun Wu, Chuang Wang, Zirui Zhou, Tianwei Cai, Wen Tao, Shidong Zuo, Chi Zhang, Yuhao Dong, Yi Feng, Qingbo Huang, Baojun Wang, Xin Ma, Haoli Ma, Xu Zhang, Yan Huang   +15 more
wiley   +1 more source

Epidemiology of Early-Onset Colorectal Cancer: A Systematic Review and Meta-Analysis of Incidence, Temporal Trends, and Associated Factors. [PDF]

Cureus
Ahmad M, Talpur AS, Solangi Z, Qadri H, Talat F, Chauhan N, Becirovic F, Roosevelt A, Azeem M, Tabassum A, Mahboob MJ, Usman H, Naseer-Ud-Din SM, Siddiqui A, Muhammad L, Ben Selma A, Javaid T.   +16 more
europepmc   +1 more source

ZBTB11 Promotes Breast Cancer Progression by Activating FBXO28‐Mediated MST1 Degradation and Suppressing Hippo Signaling

Advanced Science, EarlyView.
ZBTB11 is identified as an oncogenic transcription factor that activates FBXO28 in breast cancer. FBXO28 promotes K48‐linked ubiquitination and degradation of MST1, suppressing Hippo signaling and enhancing epithelial–mesenchymal transition and metastasis. This transcription‐to‐ubiquitination cascade defines a prognostic biomarker axis and highlights a
An Xu, Xiang‐Nan Xu, Xiao Huang, Zhou Luo, Chun‐Lian Li, Yang Du, Cheng Yan, Xiao‐Jie Yu, Jian‐Wen Wang, Long‐Di Yao, De‐Yuan Fu   +10 more
wiley   +1 more source

The Future of Vaccines. [PDF]

Vaccines (Basel)
Rijkers GT.
europepmc   +1 more source

Outdoor pastimes of an American hunter, by Theodore Roosevelt.

T. Roosevelt
semanticscholar   +1 more source

CA9‐Targeted PET Imaging for Noninvasive Discrimination of Clear Cell Renal Cell Carcinoma and Associated Tumor Biological Features

Advanced Science, EarlyView.
CA9‐targeted PET imaging could be a noninvasive approach to characterize clear cell renal cell carcinoma and associated tumor biology. PET uptake correlates with tumor CA9 expression and is linked to angiogenic activity, immune remodeling, and metabolic reprogramming.
Kailei Chen, Sixuan Cheng, Jian Shi, Ruijie Liu, Yilong Wu, Xin Zheng, Xinlun Song, Yunxuan Zhang, Lei Liu, Zhihao Wei, Qi Wang, Xinwei Li, Zirui Dong, Yuenan Liu, Hongmei Yang, Xiaoli Lan, Chunxia Qin, Dawei Jiang, Keshan Wang, Xiaoping Zhang   +19 more
wiley   +1 more source

Activation-Controlled Structural Integrity in A520 MOF Membranes for Efficient CO₂/N₂ and CO₂/CH₄ Separation. [PDF]

ACS Appl Mater Interfaces
Chi LT, Hsiao LW, Chuang CH, Kang DY.
europepmc   +1 more source

Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform Toward Non‐Invasive Diagnostics

Advanced Science, EarlyView.
Maximizing Nanoscale Disorder in Block Copolymers for Orientation‐Independent SERS Platform toward Non‐Invasive Diagnostics is a nature‐inspired strategy that engineers controlled randomness within block copolymer lamellae to achieve optical isotropy without compromising nanoscale periodicity.
Jin Man Kim, Wonsik Kim, Wansun Kim, Yeon‐Hee Kim, Samjin Choi, Jang Hwan Kim, Hyeong Min Jin   +6 more
wiley   +1 more source

Correction: A bis-macrocyclic peptide ligand mimicking the β-sandwich active site of multicopper oxidases.

Dalton Trans
Dang VT, Drena A, Telser J, Wofford L, Nguyen AI.   +4 more
europepmc   +1 more source

High Gingival Bleeding Burden in Late Pregnancy Is Associated with a Salivary Profile of Inflammatory, Regulatory, and Stress-Response Signals. [PDF]

Life (Basel)
Foratori-Júnior GA, Paz HES, Bastos RDS, Paranhos LR, Bostanci N, Buzalaf MAR, Carpenter GH.   +6 more
europepmc   +1 more source