Results 181 to 190 of about 298,662 (304)

Indigenous Knowledge and Community-Derived Counts Produce Robust Wildlife Population Estimates: Roosevelt Elk in Karuk Aboriginal Territory. [PDF]

Ecol Evol
Connor T, Montealegre-Mora F, Saxon BJ, Camarena J, Sarna-Wojcicki D, de Bruyn M, Calhoun KL, Martinez CC, Tripp E.   +8 more
europepmc   +1 more source

3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species

Advanced Science, EarlyView.
ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu, Chenhui Han, Cheng Xue, Manyi Sun, Bobo Song, Yongsong Xue, Guangyan Yang, Shaozhuo Xu, Wei Wei, Jiaming Li, Runze Wang, Jun Wu   +11 more
wiley   +1 more source

Franklin Delano Roosevelt [PDF]

American Journal of Public Health and the Nations Health, 1945
openaire   +2 more sources

Estimating the undetected burden and the likelihood of strain persistence of drug-resistant Neisseria gonorrhoeae. [PDF]

Am J Epidemiol
Oliveira Roster KI, Rönn MM, Elder H, Gift TL, Roosevelt KA, Salomon JA, Hsu KK, Grad YH.   +7 more
europepmc   +1 more source

SMAD4 Palmitoylation Drives a Metabolic‐Transcriptional Circuit to Promote Tumorigenesis and Confers Radiosensitivity in Pancreatic Cancer

Advanced Science, EarlyView.
This study identifies palmitoylation as a novel regulatory modification of SMAD4, mediated by ZDHHC22/APT2. It activates fatty acid synthesis, creating a self‐reinforcing SMAD4–FASN–palmitate feedback loop that drives pancreatic cancer growth and enhances radiotherapy sensitivity.
Yang Wang, Shan Zhang, Junping Bai, Xiaobing Li, Yi Han, Min Ji, Chongyi Jiang, Xiaobei Ge, Tianyu Yu, Yongying Hou, Jun Zhang, Wangting Li, Yiran Song, Jiaying Cai, Yingqun Zhou, Liwei An, Feng Wang   +16 more
wiley   +1 more source

Comparison of minimally invasive versus open spinopelvic fixation for unstable sacral fractures. [PDF]

J Orthop Surg Res
Hriň T, Gajdoš R, Šváč J, Botka M, Uhliarová B, Váhovský R, Čaniga J, Chandoga I, Kilian M.   +8 more
europepmc   +1 more source

Inhibition of SIRT7 Overcomes Radioresistance in Pancreatic Neuroendocrine Tumors by Reactivating MEN1 Expression

Advanced Science, EarlyView.
Pancreatic neuroendocrine tumors frequently silence MEN1 through epigenetic mechanisms. Here, SIRT7 recruits DNMT1 to the MEN1 promoter, drives hypermethylation, and enhances DNA repair. Inhibiting SIRT7 restores MEN1, reduces MRN complex abundance, impairs double‐strand break repair, and sensitizes PanNET models to radiation, supporting SIRT7 as a ...
Jianyun Jiang, Yan Wang, Yi Qin, Luohai Chen, Xiaowu Xu, Guixiong Fan, Desheng Jing, Miaoyan Wei, Xianjun Yu, Junfeng Xu, Shunrong Ji, Jie Chen   +11 more
wiley   +1 more source

Author's Reply: Critical Limitations in Systematic Reviews of Large Language Models in Health Care. [PDF]

J Med Internet Res
Python A, Li H, Fu JF.
europepmc   +1 more source

Tumor‐Derived Alpha‐1 Antitrypsin Promotes Liver Metastasis of Colorectal Cancer Through the Neutrophil Extracellular Traps–CCDC25 Pathway

Advanced Science, EarlyView.
ABSTRACT Liver metastasis is a leading cause of mortality in colorectal cancer (CRC), where the inflammatory tumor microenvironment, specifically neutrophil infiltration, significantly promotes metastatic colonization. This study reveals a pro‐metastatic role for alpha‐1 antitrypsin (A1AT) in CRC liver metastasis via a dual mechanism involving ...
Qian Fei, Chunning Li, Lei Zhan, Xiaoyan Li, Yan Hui, Yue Jin, Jing Zhang, Lu Yang, Xin Sun, Xiaoxi Li, Qian Dong, Jingdong Zhang   +11 more
wiley   +1 more source

NanoPrePro: a fully equipped, fast, and memory-efficient preprocessor for nanopore transcriptomic sequencing. [PDF]

Brief Bioinform
Chu CC, Yu JH, Kuo SC, Yang FW, Lin CC, Chen CH, Wu YC, Shih C, Sun YH, Mai TL, Chen YL, Lin HH, Su JC, Lin YJ.   +13 more
europepmc   +1 more source