Results 51 to 60 of about 295,445 (314)
Entre ciência e aventura: considerações em torno da Expedição Roosevelt-Rondon
Fronteiras, 2016 O presente texto procura fazer um balanço dos resultados da Expedição Roosevelt-Rondon, a propósito do seu centenário lembrado recentemente. Evidencia que Roosevelt oscila entre ideias de preservação e o prazer das caçadas, apontando, também,
João Klug
doaj
, 2012 Review of James Rusbridger, Betrayal at Pearl Harbour: How Churchill Lured Roosevelt into World War II and Bradley Smith Eric Nave: The Ultra-Magic Deals and the Most Secret Special Relationship, 1940 ...
Stafford, David
core +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Cuadernos de Historia de EspañaEste artículo analiza qué tipo de ayuda brindaron Franklin D. Roosevelt y Eleanor Roosevelt a la población civil y al Gobierno republicano durante la Guerra Civil española (1936 -1939), teniendo en cuenta la decisión que había tomado el Gobierno ...
María Luz Arroyo Vázquez
doaj +1 more source
The War on Terror is Over--Now What? Restoring the Four Freedoms as a Foundation for Peace and Security [PDF]
, 2009 This article observes that the Global War on Terror as an organizing concept has been abandoned and proposes that the Obama Administration restore FDR\u27s Four Freedoms in its ...
Shulman, Mark R.
core +1 more source
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
European Journal of American Studies, 2015 Theodore Roosevelt enjoys a positive reputation as an innovative and progressive politician. He was the first president in office to explicitly link immigration with the changing welfare system in the United States. Sensing that a system run by the state
Hans Krabbendam
doaj +1 more source
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Eleanor Roosevelt’s Radio Broadcasts in France
European Journal of American Studies, 2017 Eleanor Roosevelt wrote books, thousands of newspaper and magazine articles and was a regular broadcaster. Among the radio programs she hosted, and appeared on, were several for the Voice of America.
Anya Luscombe
doaj +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source