Genotypic Variation in Maize Root Hydrotropism and Its Association with Shoot Growth and Water Use Efficiency Under Partial Root-Zone Drying. [PDF]
Plants (Basel)Guan Y +8 more
europepmc +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Impact of laser-assisted and different pre-treatment modalities on dentin surface interface and bond strength of fiber posts (In-vitro study). [PDF]
Head Face MedAboElhassan RG, Eltaweel AM.
europepmc +1 more source
Molecular Oncology, EarlyView.BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi +11 more
wiley +1 more source
Medial Meniscus Root Repair Is Associated With Superior Outcomes As Compared With Partial Medial Meniscectomy at Minimum 5 Years: A Systematic Review and Meta-analysis. [PDF]
Orthop J Sports MedDean RS +3 more
europepmc +1 more source
Astrocyte heterogeneity in brain metastases
Molecular Oncology, EarlyView.Astrocytes emerge as pivotal regulators of metastatic colonization, survival, immune remodeling, and therapy response associated with an increasing heterogeneity that requires spatially and longitudinally resolved approaches to uncover regulatory programs and guide context‐specific therapies.
Carolina Hernández‐Oliver +2 more
wiley +1 more source
Diversity of <i>Fusarium</i> Species Causing Storage Rot of Table Beet in the Moscow Region of the Russian Federation. [PDF]
J Fungi (Basel)Vetrova S +5 more
europepmc +1 more source
From tumor‐centric to ecosystem‐based hypotheses in brain tumor research and care
Molecular Oncology, EarlyView.Primary brain tumors, whether in adults or children, present a major challenge because of their dramatic prognosis and the ongoing lack of efficient therapeutic approaches. In recent years, a shift has occurred from tumor‐centric concepts to a more holistic view of these tumors as dynamic ecosystems.
Julie Gavard +8 more
wiley +1 more source
Diversity and composition of root-associated fungal communities in critically small population of <i>Cypripedium subtropicum</i>. [PDF]
Front Plant SciHua M, Jiang H, Yuan R, Kong J.
europepmc +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source