Results 241 to 250 of about 1,760,983 (303)

Genetic dissection of root traits in barley identifies major QTLs and domestication signature. [PDF]

Plant Cell Rep
Sangiorgi G, Forestan C, Camerlengo F, Sciara G, Bozzoli M, Fricano A, Tondelli A, Fusi R, Bhosale R, Tuberosa R, Salvi S.   +10 more
europepmc   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

Molecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Telomere-to-telomere genome of Stylosanthes guianensis uncovers symbiotic adaptation to phosphorus-deficient soils. [PDF]

Genome Biol
Liu P, Liu C, Pu W, Zhang J, Xu R, Liu L, Luo J, Huang R, Jiang L, Huan H, Luo L, Liu G, Dong R, Chen Z.   +13 more
europepmc   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Regenerative Endodontics Maintained Arrest of External Inflammatory Root Resorption After Secondary Concussion Injury: A Case Report. [PDF]

Case Rep Dent
Wang Y, Ouyang T, Ma Z, Li X, Chen S, Chen T.   +5 more
europepmc   +1 more source

Genome-wide identification of the ABC gene family in sweet potato and its expression profiles in response to iron, aluminum, zinc, and copper stresses. [PDF]

Front Plant Sci
Gao F, Lin Y, Zhao J, Shahid M, Khan L, Li Y, Zhou X, Si C.   +7 more
europepmc   +1 more source

The Role of <i>Trichoderma harzianum</i> Elicitor <i>Hyd1</i> in Inducing the Maize Endophytic Microbial Community and <i>Bacillus</i> Strains Against Maize Root Rot. [PDF]

J Fungi (Basel)
Si G, Zhang X, Zhang C, Li Y, Wang X, Guo N, Chen J.   +6 more
europepmc   +1 more source

Nutrient acquisition of an underground and mycoheterotrophic orchid. [PDF]

AoB Plants
Flores-Borges DNA, Sisti LS, Antunes C, Brum M, Máguas C, Mayer JLS.   +5 more
europepmc   +1 more source