Results 261 to 270 of about 5,860,679 (396)
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Effects of Different Varieties of <i>Camellia oleifera</i> on Root-Associated Bacterial Community Structure and Co-Occurrence Network. [PDF]
Zhou J +6 more
europepmc +1 more source
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Root contraction does not increase long-term population growth in <i>Pediocactus bradyi</i>, an endangered cactus of Northern Arizona. [PDF]
Rojas-Pimentel J +2 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Investigating the Role and Response of Root Groups of <i>Hordeum vulgare</i> subsp. <i>spontaneum</i> Germplasm to Drought Stress. [PDF]
Shirvani H +5 more
europepmc +1 more source
Evaluating the Restoration of External Root Resorption Under Biomechanical Stress: A Finite Element Analysis [PDF]
Şevval Çelebi, Hesna Sazak Öveçoğlu
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source

