Results 41 to 50 of about 1,285,891 (313)

Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases

open access: yesFEBS Letters, EarlyView.
Accurate protein synthesis is crucial for life. The key players are aminoacyl‐tRNA synthetases (AARSs), which read the genetic code by pairing cognate amino acids and tRNAs. AARSs establish high amino acid selectivity by employing physicochemical limits in molecular recognition.
Igor Zivkovic   +2 more
wiley   +1 more source

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Hairy Roots of Scutellaria spp. (Lamiaceae) as Promising Producers of Antiviral Flavones

open access: yesMolecules, 2021
We measured and studied the growth parameters and the qualitative and quantitative composition of the flavones of hairy roots of the Scutellaria genus: S. lateriflora, S. przewalskii and S. pycnoclada.
Anna Yurievna Stepanova   +5 more
doaj   +1 more source

Thermostable neutral metalloprotease from Geobacillus sp. EA1 does not share thermolysin's preference for substrates with leucine at the P1′ position

open access: yesFEBS Letters, EarlyView.
Knowing how proteases recognise preferred substrates facilitates matching proteases to applications. The S1′ pocket of protease EA1 directs cleavage to the N‐terminal side of hydrophobic residues, particularly leucine. The S1′ pocket of thermolysin differs from EA's at only one position (leucine in place of phenylalanine), which decreases cleavage ...
Grant R. Broomfield   +3 more
wiley   +1 more source

Roots and Root Function: Introduction

open access: yesVadose Zone Journal, 2008
Eleven years ago, in a review article, [Clothier and Green (1997)][1] assessed the hydrologic budget at the land surface and pronounced that plant roots are “the big movers of water and chemical” in the vadose zone.
Peter J. Shouse, Todd H. Skaggs
openaire   +2 more sources

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Characterization of Cover Crop Rooting Types from Integration of Rhizobox Imaging and Root Atlas Information

open access: yesPlants, 2019
Plant root systems are essential for sustainable agriculture, conveying resource-efficient genotypes and species with benefits to soil ecosystem functions. Targeted selection of species/genotypes depends on available root system information.
Gernot Bodner   +4 more
doaj   +1 more source

The Roots of Psychotherapy

open access: yesSouthern Medical Journal, 1953
Mode of access: Internet.
Whitaker, Carl A.   +1 more
openaire   +2 more sources

The Syntax of Roots and the Roots of Syntax [PDF]

open access: yes, 2014
AbstractThis volume brings together chapters that discuss the nature of roots, the core elements of word meaning. It looks not only at their syntax, but also their phonology, semantics, and morpho-phonological role (or lack thereof), insofar as these do turn out to bear on their interaction with syntax. To what degree these roots carry syntactic and/or
Hagit Borer   +2 more
openaire   +2 more sources

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