Results 51 to 60 of about 130,972 (261)

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

Integrated analysis of potential microbial consortia, soil nutritional status, and agro-climatic datasets to modulate P nutrient uptake and yield effectiveness of wheat under climate change resilience

Frontiers in Plant Science, 2023
Climate change has a devastating effect on wheat production; therefore, crop production might decline by 2030. Phosphorus (P) nutrient deficiency is another main limiting factor of reduced yield.
Mahreen Yahya, Maria Rasul, Maria Rasul, Sayed Zajif Hussain, Adil Dilawar, Adil Dilawar, Midrar Ullah, Lubna Rajput, Aftab Afzal, Muhammad Asif, Tesfaye Wubet, Tesfaye Wubet, Sumera Yasmin   +12 more
doaj   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Regulating root structure of potted lettuce to magnify absorption from APP and UAN fertilizers

Frontiers in Plant Science
IntroductionImprovement of root architecture is crucial to increasing nutrient acquisition.MethodsTwo pot experiments were conducted to investigate the effects of different concentrations of urea ammonium nitrate solution (UAN) and ammonium polyphosphate
Changqing Li, Changqing Li, Yahao Li, Yahao Li, Jungang Yang, Bingrui Lian, Jiqing Wang, Guoyuan Zou   +7 more
doaj   +1 more source

Appropriate nitrogen application enhances saponin synthesis and growth mediated by optimizing root nutrient uptake ability

Journal of Ginseng Research, 2020
Background: Cultivation of medicinal crops, which synthesize hundreds of substances for curative functions, was focused on the synthesis of secondary metabolites rather than biomass accumulation. Nutrition is an important restrict factor for plant growth
Wei Wei, Chen Ye, Hui-Chuan Huang, Min Yang, Xin-Yue Mei, Fei Du, Xia-Hong He, Shu-Sheng Zhu, Yi-Xiang Liu   +8 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Blue Light Regulates Phosphate Deficiency-Dependent Primary Root Growth Inhibition in Arabidopsis

Frontiers in Plant Science, 2020
Plants have evolved mechanisms to improve utilization efficiency or acquisition of inorganic phosphate (Pi) in response to Pi deficiency, such as altering root architecture, secreting acid phosphatases, and activating the expression of genes related to ...
Chuan-Ming Yeh, Chuan-Ming Yeh, Chuan-Ming Yeh, Koichi Kobayashi, Sho Fujii, Hidehiro Fukaki, Nobutaka Mitsuda, Masaru Ohme-Takagi, Masaru Ohme-Takagi   +8 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

ADVENTITIOUS ROOTS DEVELOPMENT AND ROOT SYSTEM ARCHITECTURE OF CHRYSANTHEMUM CUTTINGS

Journal of Plant Development, 2018
Chrysanthemum have significant ornamental value and thus have a great economic importance and are also subjected to losses due to the insufficient rooting of the cuttings - the main method of vegetative propagation practiced for this crop. Insufficient understanding of the mechanisms that control adventitious root formation prevents the use of reliable
Ana COJOCARIU, Elena-Liliana CHELARIU, Cătălin TĂNASE   +2 more
openaire   +2 more sources