Results 101 to 110 of about 88,102 (312)

Treatment strategy analysis and prevalence of root canal variation of maxillary second molars from a native Chinese population

口腔疾病防治
The anatomical morphology of root canal systems in maxillary second molars (MSMs) is complex and shows diverse variations, which leads to challenging root canal treatments that could end in failure.
FENG Xiaoli, SUN Shuyu
doaj   +1 more source

Penetration of Sodium Hypochlorite Modified with Surfactants into Root Canal Dentin [PDF]

, 2016
Flavio Palazzi, Andrea Blasi, Zahed Mohammadi, Massimo Del Fabbro, Carlos Estrela   +4 more
openalex   +1 more source

Targeting Lactate and Lactylation in Cancer Metabolism and Immunotherapy

Advanced Science, EarlyView.
Lactate, once deemed a metabolic waste, emerges as a central regulator of cancer progression. This review elucidates how lactate and its epigenetic derivative, protein lactylation, orchestrate tumor metabolism, immune suppression, and therapeutic resistance.
Jiajing Gong, Yuhang Xie, Zhijie Weng, Yongzhi Wu, Longjiang Li, Bo Li   +5 more
wiley   +1 more source

An in-vitro comparative evaluation for detection of residual gutta-percha after root canal retreatment with four different files using stereo microscope

, 2022
R. Tejasree Rathod, Satyanarayana Reddy Poreddy, Satyanarayana Reddy Poreddy, G. Durgabhavani, Prasanthi Gonapa, Gopal Thodsam, B. Rajendra Prasad   +6 more
openalex   +1 more source

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

Unpredictable Root Canal Morphology: Expect the Unexpected

Advances in Human Biology, 2015
Background: A maxillary first molar with more than four canals is an interesting example of anatomic variations, especially when two of these canals are detected, with separate apical foramen in the distal root.
Sohez J Makani, Kiran Vachhani, Kailash Attur, Shoba Fernandes   +3 more
doaj  

An Insulin‐Exosome‐TNFAIP8 Axis Drives Stromal Fibrosis and Therapeutic Resistance in Pancreatic Cancer

Advanced Science, EarlyView.
In pancreatic ductal adenocarcinoma (PDAC), insulin is associated with activation of PI3K/AKT–RAB3A signaling and enhanced secretion of TNFAIP8‐enriched exosomes from tumor cells. Uptake of these exosomes by fibroblasts is linked to TRIM21‐dependent STAT1 degradation and the emergence of myofibroblastic CAF–associated features, accompanied by increased
Zhenyu Li, Li Chen, Tao Wang, Haiyang Jiang, Huijuan Wang, Mengyu Li, Guanpeng Xie, Chunhua Xi, Han Yan, Chunhui Lu, Chenchen Li, Hanyu Zhu, Feihu Sun, Lingdi Yin, Jun Yu, Yi Miao   +15 more
wiley   +1 more source

Two Rooted Mandibular First Molar with Three Distal Canals - A Case Report

Advances in Human Biology, 2014
Background: The Mandibular first molar is the tooth that requires root canal treatment most often. It usually has two roots with two canals mesially and one or two canals distally.
L R Surendra, Y NarendraNath Reddy, E Sivaprasad Reddy, D Ramaraju, T Yehoshuva Reddy   +4 more
doaj  

Formulation and Evaluation of a Novel Irrigant for the Disinfection of Root Canals Using a Candida albicans Biofilm Model

, 2013
Dustin S. Reynolds
openalex   +2 more sources

Decoding the Integrated Stress Response of Pancreatic Cancer: Identifying a Serine‐dependent Tumor Subset Under Metabolic Relationships With CAFs.

Advanced Science, EarlyView.
Researchers identified a pancreatic cancer subset with low global protein synthesis but heightened translation of stress‐response genes like ATF4, rendering cells resistant to chemotherapy and apoptosis. These tumors depend on serine and cysteine from surrounding cancer‐associated fibroblasts (CAFs), which shift to produce serine by curbing collagen ...
Sauyeun Shin, Mehdi Liauzun, Jacobo Solorzano, Morgane Le Bras, Christine Jean, Benjamin Fourneaux, Margaux Dore, Lea Fevrier, Ismahane Belhabib, Alexia Brunel, Cindy Neuzillet, Marion Larroque, Carine Joffre, Stephane Rocchi, Nicolas Fraunhoffer, Aurelie Perraud, Muriel Mathonnet, Vera Pancaldi, Laetitia Linares, Juan Iovanna, Nelson Dusetti, Ola Larsson, Remy Nicolle, Stephane Pyronnet, Corinne Bousquet, Yvan Martineau   +25 more
wiley   +1 more source