Results 121 to 130 of about 1,509,050 (359)

Tailoring Vascular‐Immune Homeostasis via Manganese‐DNA Complex‐Armed Immunogenic Extracellular Vesicles for Pancreatic Cancer Immunotherapy

open access: yesAdvanced Science, EarlyView.
This study demonstrates that Mn2⁺–tumor DNA complexes encapsulated in dendritic cell (DC)– derived immunogenic extracellular vesicles (EVDC@Mn‐DNA) act as a DC‐specific cGAS– STING activator. EVDC@Mn‐DNA treatment enhances intratumoral DC activation, improves tumor vascular function, promotes CD8⁺ T cell activity, and suppresses pancreatic tumor growth,
Xue Jiang   +13 more
wiley   +1 more source

Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development

open access: yesAdvanced Science, EarlyView.
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen   +11 more
wiley   +1 more source

Unpredictable Root Canal Morphology: Expect the Unexpected

open access: yesAdvances in Human Biology, 2015
Background: A maxillary first molar with more than four canals is an interesting example of anatomic variations, especially when two of these canals are detected, with separate apical foramen in the distal root.
Sohez J Makani   +3 more
doaj  

Auditory Hair Cell Mechanotransduction Channels Dynamically Shape the Mechanical Properties of Their Membrane Environment

open access: yesAdvanced Science, EarlyView.
This work shows, for the first time, that the stereocilia membrane in cochlear hair cells is dynamically regulated by the mechanotransduction channel to impact the membrane mechanical properties. This work provides direct evidence that the opening and closing associated with the MET channel is regulating the membrane viscosity suggesting that the MET ...
Shefin S. George, Anthony J. Ricci
wiley   +1 more source

Two Rooted Mandibular First Molar with Three Distal Canals - A Case Report

open access: yesAdvances in Human Biology, 2014
Background: The Mandibular first molar is the tooth that requires root canal treatment most often. It usually has two roots with two canals mesially and one or two canals distally.
L R Surendra   +4 more
doaj  

De Novo Gene Transcription of Connexin Mediates Cytoplasmic Fluid Exchange and Flocking Transitions in Physiological and Cancerous Epithelial Systems

open access: yesAdvanced Science, EarlyView.
EGF‐induced de novo transcription of connexins Cx26 and Cx31 promotes flocking behavior that fluidizes epithelia and enables coordinated collective migration. Connexin‐driven cytoplasmic exchange mechanistically links growth‐factor signaling to invasive dynamics.
Hind Abdo   +18 more
wiley   +1 more source

Effect of the type of endodontic sealer on the bond strength between fiber post and root wall dentin.

open access: yesFrontiers in Dentistry, 2014
An important factor that interferes with the bonding between the root canal wall and resin cement is the root canal sealer remnant. There is controversy about the effect of eugenol-containing sealers on the bond strength between resin cements and fiber ...
Ramin Mosharraf, Sepideh Zare
doaj  

Maxillary First Molar with Three Canals in Mesio-buccal Root: A Case Report

open access: hybrid, 2023
Abdullah Al Mahmud   +5 more
openalex   +2 more sources

Home - About - Disclaimer - Privacy