Results 131 to 140 of about 1,454,360 (340)
Presbycusis: Pathology, Signal Pathways, and Therapeutic Strategy
In ARHL, the stria vascularis, acting as a cochlear battery, gradually loses its ability to maintain the endocochlear potential, leading to impaired hair cell function and progressive hearing loss. Single‐cell sequencing reveals age‐related cellular changes in the cochlea, providing insights into the underlying mechanisms of aging and potential ...
Xiaoxu Zhao+12 more
wiley +1 more source
LRRC8A Regulates Outer Hair Cell Volume and Electromotility and is Required for Hearing
This study identifies LRRC8A‐dependent volume‐regulated anion channels (VRACs) as essential for cochlear outer hair cells' electromotility and auditory signal amplification. LRRC8A deficiency disrupts cell volume control, impairs auditory sensitivity, and causes deafness, while targeted LRRC8A re‐expression restores auditory function.
Shengnan Wang+15 more
wiley +1 more source
The Reconstruction of Peripheral Auditory Circuit: Recent Advances and Future Challenges
This paper summarizes the potential of biomaterials, stem cells, and gene editing technologies in the regeneration of inner ear hair cells, spiral ganglion neurons, and inner ear organoids. Challenges and potential developments are discussed and explored.
Zhe Li+3 more
wiley +1 more source
LincNEAT1 Encoded‐NEAT1‐31 micropeptide directly binds with Aurora‐A and enhanced AKT pathways to pormotes phagocytosis against multi cancer cells. Abstract Macrophages play vital roles in innate and adaptive immunity, and their essential functions are mediated by phagocytosis and antigen presentation.
Jie Li+8 more
wiley +1 more source
OCCURRENCE OF TECHNICAL ERRORS IN ENDODONTICALLY TREATED TEETH: A RADIOLOGICAL STUDY
Aim. The aim of study was to assess the quality of root canal fillings and occurrence of various categories of technical errors in patients with endodontically treated teeth. Materials and method.
Mihaela Sălceanu+6 more
doaj
A STUDY ON THE EFFECT OF ROOT-CANAL DISINFECTANTS ON ACRYLIC RESIN (REP 1)
Hakubu Yamamoto+5 more
openalex +2 more sources
A ‘one‐bottle’ adhesive system for bonding a fibre post into a root canal: an SEM evaluation of the post–resin interface [PDF]
Marco Ferrari, Francesco Mannocci
openalex +1 more source