Results 141 to 150 of about 2,043,462 (275)

Bio‐Memristor Based on Clinical Bile Samples: A Proof‐of‐Concept Pilot Study for Detection of Gallbladder Cancer

open access: yesAdvanced Science, EarlyView.
In this work, we present a bile‐based memristor hardware framework that enables direct, label‐free identification of cholelithiasis and gallbladder cancer at the device level. The Ag/bile/FTO memristor features stable resistive switching and disease‐specific electrical responses, providing a conceptual foundation for circuits and an integrated ERCP ...
Junming Zhu   +17 more
wiley   +1 more source

Root Canal Morphology of Mandibular Permanent Incisors - A Cone-Beam Computed Tomographic (CBCT) Study

open access: yesJournal of College of Medical Sciences-Nepal
Background Proper knowledge of root canal anatomy is most important for the success of root canal treatment. The objective of this study to find the numbers and morphological characteristics of root and root canals of mandibular central and lateral ...
Pujan Kranti Kayastha   +3 more
doaj   +1 more source

Integrated Multi‐Omics Reveals Cellular States and Microenvironmental Remodeling in Coexisting DCIS and IDC

open access: yesAdvanced Science, EarlyView.
Coexisting DCIS and IDC samples are profiled using spatial transcriptomics, single‐cell RNA sequencing, and single‐cell DNA sequencing. Integrative multi‐omics analysis reveals distinct malignant epithelial and microenvironmental features between DCIS and IDC, which are further validated using Xenium and multiplex immunohistochemistry.
Ning Zhang   +18 more
wiley   +1 more source

Assessing root canal anatomy of canine teeth and prevalence of impacted canines in a Saudi Arabian subpopulation through cone-beam computed tomography imaging

open access: yesFolia Morphologica
BACKGROUND: Canines play a crucial role in arch development, dental aesthetics, and occlusal function. Variations in root canal morphology can considerably impact upon root canal treatment outcomes. Therefore, the aim of this study was to assess the root
Ahmad Hassan Jabali
doaj   +1 more source

Tracking CDK1 Dynamics With a Novel Biosensor Mouse and Clinical Cohorts to Predict CDK4/6 Inhibitor Sensitivity in ER+ Breast Cancer

open access: yesAdvanced Science, EarlyView.
Cyclin‐dependent kinase (CDK) 1 activity is a dynamic marker of treatment response in estrogen receptor positive breast cancer. Patient cohorts reveal CDK1 activity increases during progression to invasive disease, where high expression correlates with poor survival. Using a novel Cdk1 biosensor mouse alongside in vitro models, we demonstrate that CDK1
Sarah Alexandrou   +17 more
wiley   +1 more source

CANAL CONFIGURATION IN THE ROOTS OF MAXILLARY SECOND PREMOLAR: A CLINICAL STUDY

open access: yesJournal of Evolution of Medical and Dental Sciences, 2012
Modified access cavity preparation and X ray- interpretation were used clinically to find out the additional canals in the root of maxillary second premolars. In 85% of the case two canals were located and treated, of these 30% had two separate apical foramen and 50.66% had two canal, joined at the apical third in 5% of the cases, two roots with two ...
openaire   +1 more source

Root Canal Anatomy of Maxillary First and Second Permanent Molars in a Sudanese population:An invitro study

open access: yes, 1996
The aim of this study was to describe root canal anatomy of maxillary first and second permanent molars in a Sudanese population and to investigate the effectiveness of probing, troughing and magnification when locating the second mesiobuccal canal in
Mohammad Hassan, Nizar
core  

GSLR Drives Lung Adenocarcinoma as a Critical Regulator of Energy Homeostasis Through Creatine Kinase B Activation

open access: yesAdvanced Science, EarlyView.
This study identifies the glucose/glutamine sensitive lncRNA GSLR as a driver of lung adenocarcinoma progression. Nutrient restriction reduces chromatin accessibility at the GSLR locus and blocks CTCF‐mediated transcriptional regulation. GSLR directly interacts with DHX9 and recruits it to the CKB promoter, arresting R‐loop accumulation and promoting ...
Xinyi Qian   +9 more
wiley   +1 more source

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