Results 151 to 160 of about 70,661 (389)

Precision‐Engineered Silver Single‐Atom Carbon Dot Nanozymes for Theranostic Management of Acute Kidney Injury

open access: yesAdvanced Science, EarlyView.
Mitochondria‐targeted silver single‐atom carbon dot (T‐AgSA‐CDs) nanozymes enable dual SOD/GPx‐like ROS scavenging, real‐time imaging, and therapeutic effects for acute kidney injury (AKI). Atomically dispersed Ag sites synergize with carbon dots to restore renal redox hemostasis, protect mitochondrial function, mitigate inflammation, facilitate post ...
Tianle Tang   +10 more
wiley   +1 more source

Evaluation of the Antibacterial Activity of Triclosan-incorporated Root Canal Filling Materials for Primary Teeth against Enterococcus faecalis. [PDF]

open access: yesInt J Clin Pediatr Dent, 2021
Deepak BM   +5 more
europepmc   +1 more source

Dual Aptamers‐Based SETDB1 PROTACs as Effective Anti‐Tumor Strategies for Breast Cancer

open access: yesAdvanced Science, EarlyView.
This study establishes dual‐aptamer PROTACs targeting SETDB1 using a SETDB1‐specific aptamer conjugated to AS1411. The designed PROTACs penetrate cells, recruit MDM2 to degrade SETDB1, and inhibit cancer cell proliferation and migration. Remarkably, they also overcome tamoxifen resistance and enhance CD8+ T cell cytotoxicity, suppressing tumor growth ...
Yanxuan Guo   +6 more
wiley   +1 more source

Investigation Into the Dynamics of the Cupula in the Vestibular Organ of Adult Zebrafish Using Metabolic Glycoengineering

open access: yesAngewandte Chemie, EarlyView.
The cupula is a membrane within the vestibular organ that senses rotatory accelerations of the head. Metabolic glycoengineering in combination with bioorthogonal labeling demonstrates that in adult zebrafish – being a model for the human inner ear – this membrane is constantly renewed.
Hans Scherer   +4 more
wiley   +2 more sources

In Vitro Evaluation of Apical Sealing Ability of HEROfill® Obturator versus Cold Lateral Condensation in Curved Root Canals

open access: yesFrontiers in Dentistry, 2016
Objectives: This study aimed to assess and compare the apical sealing ability of HEROfill® Soft-Core system and lateral condensation technique in fine curved canals using the fluid filtration method.
Mina Zarei   +3 more
doaj  

Success Rate of Contemporary Regenerative Endodontic Therapy and the Expected Outcomes of the Endodontic Microsurgery: A Systematic Review and Meta-Analysis

open access: yesPesquisa Brasileira em Odontopediatria e Clínica Integrada, 2021
Objective: To examine the level of the accumulating success of the modern Resin-Based Endodontic Surgery (RES) and comparison with Endodontic Microsurgery (EMS) and finally offer a replacement at the predicted final results of EMS. Material and Methods:
Golchin Jabbari   +3 more
doaj  

Influence of Taper on the Flexibility of Nickel-Titanium Rotary Files [PDF]

open access: yes, 2014
Introduction: Modern nickel-titanium instruments have various tapers and have been marketed to have superior flexibility from previous generations. Current ISO standards require force measurements at a static point along the file.
Kingma, Christopher J.
core   +1 more source

Compensatory Interplay Between Clarin‐1 and Clarin‐2 Deafness‐Associated Proteins Governs Phenotypic Variability in Hearing

open access: yesAdvanced Science, EarlyView.
Functional compensation between clarin‐1 and clarin‐2 in cochlear hair cells. Hearing loss associated with CLRN1 mutations shows striking phenotypic variability; however, the underlying mechanisms remain poorly understood. This study reveals that clarin‐1 and clarin‐2 function cooperatively in cochlear hair cells to sustain mechanoelectrical ...
Maureen Wentling   +17 more
wiley   +1 more source

A comparative evaluation of apical microleakage of MTA fillapex and AH26 sealers in the presence of blood in the canal space of the teeth

open access: yesCaspian journal of dental research, 2014
Introduction: Apical seal in blood or dry root canal is a problem in endodontic treatment. Failure of apical seal causes inflammatory reaction and failure root canal treatment.
Ali Soleymani   +6 more
doaj  

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