Results 121 to 130 of about 52,887 (307)

Integrating Spatial Proteogenomics in Cancer Research

Advanced Science, EarlyView.
Xx xx. ABSTRACT Background: Spatial proteogenomics marks a paradigm shift in oncology by integrating molecular analysis with spatial information from both spatial proteomics and other data modalities (e.g., spatial transcriptomics), thereby unveiling tumor heterogeneity and dynamic changes in the microenvironment.
Yida Wang, Yang Wu, Feng Zhang, Parthiban Periasamy, Haiyue You, Denise Goh, Rachel Elizabeth Ann Fincham, Xin Ning, Danping Wu, Lu Liu, Ying Jiang, Zhiwen Qian, Joe Yeong, Yan Zhang   +13 more
wiley   +1 more source

A Rare Root Canal Configuration of Maxillary Second Molar: A Case Report

Case Reports in Dentistry, 2012
A thorough knowledge of root canal morphology is a prerequisite for the endodontic therapy. The maxillary molars, especially the second molars, have the most complicated root canal system in permanent dentition.
Gautam P. Badole, Rakesh N. Bahadure, M. M. Warhadpande, Rajesh Kubde   +3 more
doaj   +1 more source

Reproductive physiology of the female cat [PDF]

, 2003
Ovarian cyclicity induces considerable changes in morphology, physiology and function of the reproductive organs in animals. This thesis aimed to study reproductive physiology of the female domestic cat, focusing on the cervix, uterus and uterine tube ...
Chatdarong, Kaywalee
core  

Leveraging Macrophage Metabolic Reprogramming for Enhanced Anti‐Tumor Immunity

Advanced Science, EarlyView.
Tumor‐associated macrophages (TAMs) are key regulators of the tumor microenvironment (TME), with their metabolic states playing a critical role in tumor progression or regression. This review summarizes current understanding of TAM metabolic plasticity alongside cutting‐edge bioengineering innovations, outlining a roadmap for transforming the ...
Zhiyun Liu, Lingyao Zeng, Xulin Gan, Yilin Zhou, Han Shen, Dan Wu, Xin Shou, Minmin Jiang, Liyun Shi   +8 more
wiley   +1 more source

The life cycles of cryptogams [PDF]

, 1991
Meiosis and karyogamy are recognized as control points in the life cycle of cryptogams. The control of meiosis is evidently complex and in yeast, and by analogy in all cryptogams, involves progressive gene activation.
Bell, Peter R.
core   +2 more sources

Ammonia Detoxification Inhibits Liver Metastasis by Reshaping Hepatic Microenvironment

Advanced Science, EarlyView.
Liver metastasis diverts aspartate into hyperactive pyrimidine synthesis, disrupting urea cycling and causing pathogenic ammonia accumulation. Ammonia dually reprograms the microenvironment by: (1) activating hepatic stellate cells (HSCs) into pro‐fibrotic metastasis‐associated fibroblasts (MAFs), and (2) suppressing anti‐tumor monocytes/macrophages ...
Sumin Sun, Haili Hu, Long Chen, Yuan Gao, Peng Sun, Liming Chen   +5 more
wiley   +1 more source

Analysis of root canal morphology in mandibular incisor using micro-focus X-ray CT [PDF]

, 2014
日本歯科大学2013雑誌掲載論題 ...
西田 太郎
core  

Catechol Derivative‐Based Bioadhesives: Molecular Design for Precision Medical Adhesion

Advanced Science, EarlyView.
This study utilizes tree‐inspired side‐chain engineering to graft five catechol derivatives onto PVA, systematically revealing how side‐chain length and substituents regulate adhesion and cohesion properties. Among them, the PVA‐CA patch demonstrates superior tissue adhesion, biocompatibility, and promotes regeneration, establishing a programmable ...
Xueyu Wang, Zixin Yang, Shan Wang, Weiwei Tan, Zhirui He, Qinyu Duan, Huanan Wang, Tao Chen, Shanshan Hu   +8 more
wiley   +1 more source

Beyond Extracellular Vesicle (EV) Hype: Practical Solutions and Remaining Hurdles in EV Research, Manufacturing, and Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are nanoscale mediators of intercellular communication with diverse molecular cargoes that reflect their cell of origin. Advances in isolation, detection, and single‐particle analytics have revealed increasing molecular and functional heterogeneity, while exposing limitations in how EV identity and activity are ...
David J. Lundy, Zoe L. Chau, Sheng‐You Chen, Nanami Fujisawa, John J. Hill, Barnett M. Hsu, Joanne K. Liu, Karol W. Mai, James J. Lai   +8 more
wiley   +1 more source

Micro-computed tomographic evaluation of root and canal anatomy of maxillary first premolars in Iraqi sub-population

Scientific Reports
Successful root canal treatment requires a thorough understanding of root canal morphology. This study investigated the root canal morphology and the fine anatomical characteristics of maxillary first premolars in an Iraqi sub-population using micro ...
Abdullah Mohammed Aljawhar, Norliza Ibrahim, Azwatee Abdul Aziz, Hany Mohamed Aly Ahmed, Noor Hayati Azami   +4 more
doaj   +1 more source