Results 41 to 50 of about 3,749,574 (296)

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

Molecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche, Niels J. van Ruitenbeek, Charlotte Adang, Luke O'Gorman, Pui Yuen Lee, Willemijn M. Klein, Adriana C. H. van Engen‐van Grunsven, Jack A. Schalken, Sander Bervoets, Gerald W. Verhaegh, Carla M. L. van Herpen   +10 more
wiley   +1 more source

Root canal treatment of maxillary second molar with three mesial buccal root canals: a case report and literature review

口腔疾病防治, 2021
Objective To explore the key points of clinical diagnosis and treatment of three mesiobuccal root canals. Methods In the procedure of endodontic therapy for the upper left second molar with pulpitis, through root canal exploration under a dental ...
MEI Xiaohan, LIU Jin, HONG Tao, YOU Suxia, CHENG Xiaogang, TIAN Yu   +5 more
doaj   +1 more source

Triple antibiotic paste in root canal therapy

, 2012
The success of the endodontic treatment depends on the microbial suppression in the root canal and periapical region. Endodontic instrumentation alone cannot achieve a sterile condition.
Alagappan Meenakshi Sundaram, Ramachandran Karunakaran, Selvaraj Vinodh, Rangasamy Vijayaraghavan, Veerabathran Mahesh Mathian   +4 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

A case of maxillary second premolar with 3 teeth and 4 root canals and a literature review

口腔疾病防治, 2019
Objective To explore the discovery and treatment of multiple root canals in the maxillary second pre⁃ molar to provide a reference for root canal therapy.
LI Hong, XIN Bingchang, TENG Qi
doaj   +1 more source

Influência do operador sobre a capacidade do ROOT ZX localizar o forame apical [PDF]

, 2014
TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Ciências da Saúde. Odontologia.O objetivo deste estudo foi analisar a capacidade do ROOT ZX localizar o forame apical e verificar se essa capacidade é afetada por diferentes operadores ...
Voigt, Thaisa
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Endodontic therapy and Medication-related osteonecrosis of the jaw onset: a scoping review and expert opinion-based qualitative meta-synthesis

BMC Oral Health
Introduction Medication-related osteonecrosis of the Jaw (MRONJ) is a serious side effect of bone-modifying agents (BMAs), including bisphosphonates, denosumab, and antiangiogenic drugs.
R. Mauceri, M. Coppini, V. C. A. Caponio, F. Zamparini, C. Prati, G. Campisi   +5 more
doaj   +1 more source

Apicoetomy and Root Canal Therapy of Canine Teeth in the Dog [PDF]

, 2014
When the root canal of the canine tooth of a dog is exposed due to wear or fracture, the result may be abscessation, bone resorption, and evulsion of the alveolus.
DeYoung, D., Sick, Fred
core  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

FEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source