Results 51 to 60 of about 3,495,020 (259)

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

Comparative evaluation of fracture and defect in reciproc and rotary files in severe curved root canals

open access: yesCaspian journal of dental research, 2015
Introduction: Root canal instrumentation is an important phase in root canal therapy. Since success in endodontic treatment depends on file defect and fracture, the aim of this study was to compare the evaluation of defect and fracture in rotary and ...
Mahdis Bagherian   +6 more
doaj  

Avaliação da microdureza da dentina radicular após o uso de soluções irrigadoras e do curativo com hidróxido de cálcio [PDF]

open access: yes, 2014
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências da Saúde, Programa de Pós-Graduação em Odontologia, Florianópolis, 2014.O objetivo deste estudo foi avaliar a influência do uso de soluções irrigadoras e do uso ...
Pinto, Larissa Fernanda
core  

Micro-CT investigation of different types of rotary root canal enlargement methods

open access: yes, 2021
Biomechanical preparation of root canal is one of the main endodontic therapy steps. More recently, micro-CT has been proposed to compare the canal anatomy during preparation to give clinicians an impartial evaluation of many rotary systems in the market.
Mehrabanian, Mojtaba
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Apical instrumentation in endodontic therapy

open access: yesPadjadjaran Journal of Dentistry, 2007
Cleaning and shaping of the root canal as the foundation for successful endodontic therapy. Cleaning of the root canal as the removal of all the contents of the root canal systems before and during shaping.
Kurniasri Darliana, Endang Sukartini
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Avaliação da infiltração cervico-apical, par meio de microorganismos, atraves de canais radiculares obturados por tecnicas da guta-percha termoplastificada e condensação lateral : estudo in vitro [PDF]

open access: yes, 1998
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias da SaudeEste estudo avaliou in vitro o selamento, no sentido cérvico-apical, de canais radiculares obturados pela técnica de condensação lateral de cones de guta-percha ...
Lucena, Marcia Gonçalves
core  

Prolematics of curved root canals

open access: yes, 2023
Root canal therapy is a complex procedure that faces difficulties stemming from intricate canal structures and pronounced bends. Achieving positive outcomes relies on precise measurement of canal dimensions, skilled maneuvering within the canals, and ...
Sadeghdoost, Amirreza
core  

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

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