Results 171 to 180 of about 1,671,483 (282)

Consequence modeling and root cause analysis (RCA) of the real explosion of a methane pressure vessel in a gas refinery. [PDF]

Heliyon, 2023
Khodadadi-Mousiri A, Yaghoot-Nezhada A, Sadeghi-Yarandi M, Soltanzadeh A.   +3 more
europepmc   +1 more source

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Root cause analysis investigation of visible particulates in therapeutic protein drug products using morphologically directed Raman spectroscopy. [PDF]

Sci Rep
de Luna IF, Telikepalli SN, Carrier M, Ripple D, Srinivasan C, O'Connor T, Lute S, Bhirde A.   +7 more
europepmc   +1 more source

Identifying Contributing Factors Associated With Dental Adverse Events Through a Pragmatic Electronic Health Record-Based Root Cause Analysis. [PDF]

J Patient Saf, 2023
Kalenderian E, Bangar S, Yansane A, Tran D, Sedlock E, Xiao Y, Urata J, Olson G, Franklin A, Kookal K, Ibarra-Noriega A, Tungare S, Tokede O, Spallek H, White JM, Walji MF.   +15 more
europepmc   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source

Root Cause Analysis of Patients with Pancreatic Cancer Who Underwent Imaging Not Resulting in a Cancer Diagnosis in the 18 Months Prior to Diagnosis. [PDF]

Cancers (Basel)
Mohamed SA, Umar N, Sia M, Smyth J, Udumalagala S, Makki MU, Roberts K, Mahon B, Albazaz R, Trudgill N.   +9 more
europepmc   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source

Incidence and root cause analysis of near-miss events in medical device use errors in intensive care units using Ishikawa diagram. [PDF]

Jpn J Nurs Sci
Seong SM, Oh H, Park JS, Bae SH, Nam KC, Park SY, Kwon BS, Kim BH.   +7 more
europepmc   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Improving ICSI success rates following root cause analysis and use of system behaviour charts: the devil is in the detail! [PDF]

BMJ Open Qual, 2022
Woodland E, Carroll M.
europepmc   +1 more source