Results 81 to 90 of about 1,724,625 (294)

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

Molecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu, Nicolas J. Niklaus, Anna M. Schläfli, Igor Tokarchuk, Magali Humbert, Federico La Manna, Bich Vu, David Maul, Ramin Radpour, Marianna Kruithof‐de Julio, Inti Zlobec, Jörn Dengjel, Bruce E. Torbett, Mario P. Tschan   +13 more
wiley   +1 more source

Root coverage using epithelial embossed connective tissue graft

Indian Journal of Dental Research, 2011
In periodontal practice, root coverage after marginal soft tissue recession requires daily clinical decisions. Numerous longitudinal human studies have been presented to support the efficacy and predictability of different mucogingival surgical ...
T Ramakrishnan, Manmeet Kaur, Kriti Aggarwal   +2 more
doaj   +1 more source

A Comparison of Clinical Effect for Root Coverage

The Journal of the Korean Academy of Periodontology, 2008
Purpose: The purpose of this study was to compare clinical effect of the Langer & Langer technique , the modified Langer & Langer technique and Bruno technique. Material and Methods: 30 patients who have gingiva recession(Miller class I or class II) were carried root coverage.
Jong-Soo Han, Ki-Seok Hong, Chin-Hyung Chung, Sung-Bin Lim   +3 more
openaire   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Optimización del injerto conectivo subepitelial en la cobertura de recesiones gingivales múltiples contiguas. Presentación de un caso clínico Optimization of the subephitelial connective tissue graft to treat adjacent multiple gingival recessions. Clinical case presentation

Revista de la Asociación Odontológica Argentina, 2017
Resumen Objetivo: Describir, mediante un caso clínico, una técnica quirúrgica para la optimización del injerto conectivo libre subepitelial en la cobertura de recesiones gingivales contiguas múltiples.
Jennifer Romina Alberichi, Nelson Carranza   +1 more
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Photographs of Mary Pauline Root

, 1920
Photographs of Mary Pauline Root most likely during her time as a missionary in Japan around 1891 and while visiting American Indian communities and Indian Government Schools teaching social hygiene for the U.S. Bureau of Indian Affairs in 1920.

core  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Challenges in Root Coverage Procedure: A Narrative Review

Journal of Multidisciplinary Dental Research
In contemporary dentistry practices, root covering techniques have gained a lot of popularity. Despite the fact that these methods are thought to be safe, their surgical character may provide the clinician with a number of difficulties throughout ...
Rasal P Riyas, Anupama Rao, Shashikanth Hegde   +2 more
doaj   +1 more source

Sub-epithelial connective tissue graft for root coverage in nonsmokers and smokers: A pilot comparative clinical study

Journal of Indian Society of Periodontology, 2016
Background: Gingival recession is a common condition and is more prevalent in smokers. It is widely believed that root coverage procedures in smokers result in less desirable outcome compared to nonsmokers', and there are few controlled studies in ...
Chini Doraswamy Dwarakanath, Bheemavarapu Divya, Gottumukkala Naga Venkata Satya Sruthima, Gautami Subadra Penmetsa   +3 more
doaj   +1 more source