Results 51 to 60 of about 1,139,541 (288)
Molecular Oncology, EarlyView.In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source
Frontiers in Plant Science, 2022 Pectin, cellulose, and hemicellulose constitute the primary cell wall in eudicots and function in multiple developmental processes in plants. Root hairs are outgrowths of specialized epidermal cells that absorb water and nutrients from the soil.
Qing Zhang +9 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Analysis of the functional conservation of genes in a plant single cell type: the root hair cell [PDF]
, 2017 The evolution of plant species is tightly associated with major changes in their genome such as their allopolyploidy and autopolyploidy. These paleopolyploid events and recent genome duplications have contributed to the large sizes of the plant genomes ...
Qiao, Zhenzhen
core
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Plant, Soil and Environment, 2016 Root plasticity is important for plants to adapt to heterogeneous nutrient environments. The differential responses of six spring wheat genotypes were investigated; the plants had been subjected to deficient (2 μmol) and abundant phosphorus (P) (200 μmol)
Y.S. Wang, L.S. Jensen, J. Magid
doaj +1 more source
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Frontiers in Plant Science, 2019 Transcriptional networks are tightly controlled in plant development and stress responses. Alternative polyadenylation (APA) has been found to regulate gene expression under abiotic stress by increasing the heterogeneity at mRNA 3′-ends.
Jingyi Cao +10 more
doaj +1 more source
Root Hair Sizer: an algorithm for high throughput recovery of different root hair and root developmental parameters [PDF]
Plant Methods, 2019 The root is an important organ for water and nutrient uptake, and soil anchorage. It is equipped with root hairs (RHs) which are elongated structures increasing the exchange surface with the soil. RHs are also studied as a model for plant cellular development, as they represent a single cell with specific and highly regulated polarized elongation.
Guichard, Marjorie +3 more
openaire +5 more sources
Auxin transport through non-hair cells sustains root-hair development [PDF]
, 2009 The plant hormone auxin controls root epidermal cell development in a concentration-dependent manner. Root hairs are produced on a subset of epidermal cells as they increase in distance from the root tip.
Leyser, H.M.O +23 more
core +2 more sources